复方木尼孜其颗粒联合高光功率光子治疗轻中度痤疮的创新疗法研究  

Study on the Innovative Therapeutic Treatment of Mild to Moderate Acne by Combining Compound Muni Ziqi Granules with High Light Power Photon Therapy

作　　者：陈国卫 CHEN Guowei(Department of Dermatology,Wuxi Huishan Geriatric Hospital,Wuxi,Jiangsu Province,214174 China)

机构地区：[1]无锡市惠山区老年病医院皮肤科,江苏无锡214174

出　　处：《系统医学》2024年第5期157-160,共4页Systems Medicine

摘　　要：目的研究复方木尼孜其颗粒联合高光功率光子治疗轻中度痤疮的效果。方法选取2022年1月—2023年1月期间无锡市惠山区老年病医院皮肤科收治的250例轻中度痤疮患者为研究对象,采用随机数表法分为两组,对照组(125例)实施高光功率光子治疗,研究组(125例)实施复方木尼孜其颗粒联合高光功率光子治疗。对比两组临床疗效、皮损数目变化情况、中医证候积分、不良反应发生率。结果治疗4周后,研究组治疗总有效率(92.80%)高于对照组(84.00%),差异有统计学意义(χ^(2)=4.719,P<0.05)。治疗4周后,两组患者的粉刺数目、丘疹数目、脓包数目均减少,且研究组的粉刺数目、丘疹数目、脓包数目较对照组均更少,差异有统计学意义(P均<0.05)。治疗4周后,两组患者的中医证候积分均降低,且研究组的中医证候积分较对照组更低,差异有统计学意义(P均<0.05)。两组的不良反应发生率对比,差异无统计学意义(P>0.05)。结论复方木尼孜其颗粒联合高光功率光子用于轻中度痤疮患者治疗中的效果更佳,可显著减少皮损,控制相关症状,提高治疗效果,且安全性良好。Objective To study the effect of compound Muni Ziqi granules combined with high light power photon for the treatment of mild to moderate acne.Methods A total of 250 patients with mild to moderate acne admitted to the dermatology department of Wuxi Huishan Geriatric Hospital from January 2022 to January 2023 were selected as the study objects and were divided into two groups by random number table method.The control group(125 cases)re⁃ceived high-power photon treatment,and the study group(125 cases)received compound Munizizi granules combined with high-power photon treatment.The clinical efficacy,changes in the number of skin lesions,traditional Chinese medicine(TCM)symptom score and incidence of adverse reactions were compared between the two groups.Results After 4 weeks of treatment,the total effective rate of the study group(92.80%)was better than that of the control group(84.00%),and the difference was statistically significant(χ^(2)=4.719,P<0.05).After 4 weeks of treatment,the number of acne,pimple and pustule decreased in both groups,and the number of acne,pimple and pustule in the study group was less than that in the control group,and the difference was statistically significant(all P<0.05).After 4 weeks of treatment,the scores of TCM symptoms in both groups decreased,and the scores of TCM symptoms in the study group were lower than those in the control group,and the difference was statistically significant(both P<0.05).The incidence of adverse reactions in the two groups was no statistically significant difference(P>0.05).Conclusion The combina⁃tion of high light power photon therapy with the use of compound Muni Ziqi granules in the treatment of mild to moder⁃ate acne is more effective,which can significantly reduce lesions,control the symptoms,improve the therapeutic effect,and has good safety.

关 键 词：复方木尼孜其颗粒 高光功率光子 轻中度痤疮 疗效 

分 类 号：R758[医药卫生—皮肤病学与性病学]