医院就诊患者的糖尿病视网膜病变患病情况及相关因素分析  

Analysis of the Prevalence of Diabetic Retinopathy and Related Factors in Outpatients with Diabetes Mellitus

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作  者:程春霞 刘军[1] 谷薛姣 CHENG Chunxia;LIU Jun;GU Xuejiao(Luohe Central Hospital,Henan Luohe 462000)

机构地区:[1]漯河市中心医院,河南漯河462000

出  处:《深圳中西医结合杂志》2024年第6期26-29,共4页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

基  金:河南省医学科技攻关计划项目(20200213269)。

摘  要:目的:分析入院糖尿病(DM)患者的糖尿病视网膜病变(DR)患病情况及相关危险因素。方法:选取2021年1月至2023年8月入漯河市中心医院治疗的122例DM患者,根据眼底症状将患者分为非DR组(56例),DR组(66例)。同时将DR组分为非增生期糖尿病视网膜病变(NPDR)组(41例)和增生期糖尿病视网膜病变(PDR)组(25例)。收集122例患者的相关临床资料,采取logistic回归分析患者发生DR、PDR的影响因素。结果:(1)和非DR组患者比较,DR组患者年龄普遍较大,同时病程较长,糖化血红蛋白(HbA1c)水平较高,患有高血压及高血脂的人数占比更高,差异均具有统计学意义(P<0.05);(2)PDR组患者的病程普遍比NPDR组患者长,且身体质量指数(BMI)水平更高,同时患有高血脂的人数占比更高,差异均具有统计学意义(P<0.05)。(3)多因素logistic回归分析结果显示,病程长和HbA1c水平偏高是DM患者发生DR的危险因素(P<0.05);病程长及合并高血脂是DR患者发生PDR的危险因素(P<0.05)。结论:病程长和HbA1c水平偏高是DM患者发生DR的独立危险因素。对于已经发生DR的患者,病程长和合并高血脂是其发展为PDR的独立危险因素。Objective To analyze the prevalence of diabetic retinopathy(DR)and related risk factors in hospitalized patients with diabetes mellitus(DM).Methods A total of 122 DM patients who were treated at Luohe Central Hospital from January 2021 to August 2023 were selected.According to fundus symptoms,the patients were divided into the non-DR group(56 cases)and the DR group(66 cases).The DR group was further divided into the non-proliferative diabetic retinopathy(NPDR)group(41 cases)and the proliferative diabetic retinopathy(PDR)group(25 cases).The relevant clinical data of 122 patients were collected,and logistic regression analysis was used to analyze the factors influencing the occurrence of DR and PDR.Results(1)Compared with the non-DR group,patients in the DR group were generally older,had a longer course of disease,higher glycosylated hemoglobin(HbA1c)levels,and a higher proportion of patients with hypertension and hyperlipidemia,with statistically significant differences(P<0.05);(2)Patients in the PDR group generally had a longer course of disease and higher body mass index(BMI)levels than patients in the NPDR group,and a higher proportion of patients with hyperlipidemia,with statistically significant differences(P<0.05).(3)The results of multivariate logistic regression analysis showed that a longer course of disease and higher HbA1c levels were risk factors for the occurrence of DR in DM patients(P<0.05);A longer course of disease and comorbid hyperlipidemia were risk factors for the occurrence of PDR in DR patients(P<0.05).Conclusion A longer course of disease and higher HbA1c levels are independent risk factors for the occurrence of DR in DM patients.For patients who have already developed DR,a longer course of disease and comorbid hyperlipidemia are independent risk factors for the progression to PDR.

关 键 词:糖尿病视网膜病变 增生期糖尿病视网膜病变 影响因素分析 

分 类 号:R587.2[医药卫生—内分泌] R774.1[医药卫生—内科学]

 

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