出 处:《深圳中西医结合杂志》2024年第5期10-14,共5页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
基 金:河南省中医药科学研究专项课题(2019ZY2041)。
摘 要:目的:分析羌活胜湿汤加减结合中频脉冲电疗法在颈型颈椎病治疗中的临床价值。方法:选取2021年8月至2022年10月许昌市人民医院收治的颈型颈椎病患者96例,按随机数字表法分为联合组(48例)和单一组(48例)。单一组患者予以中频脉冲电疗法治疗,联合组患者在单一组基础上联合羌活胜湿汤加减治疗。比较两组患者临床疗效、症状消失时间(颈部功能受限、颈项僵硬、恶寒)、疼痛数字评分量表(NRS)评分、颈椎功能[颈部残障指数(NDI)、颈椎关节活动度(CROM)]评分、炎症因子[白细胞介素–6(IL–6)、IL–1β、肿瘤坏死因子–α(TNF–α)]水平及不良反应发生率。结果:联合组患者的总有效率较单一组高;联合组患者的颈部功能受限、颈项僵硬、恶寒消失时间均较单一组短;治疗1个疗程后、2个疗程后,联合组患者NRS评分较单一组低;治疗后,联合组患者的NDI评分较单一组低,CROM评分较单一组高;治疗后,联合组患者的血清IL–6、IL–1β、TNF–α水平较单一组低,上述差异均具有统计学意义(P <0.05);两组患者不良反应发生率比较,差异无统计学意义(P> 0.05)。结论:对颈型颈椎病采用羌活胜湿汤加减结合中频脉冲电疗法治疗,可提高临床效果,减少症状消失时间,减轻疼痛,促进颈椎功能恢复,减轻炎症反应,安全性良好。Objective To analyze the clinical value of modified Qianghuo Shengshi decoction combined with intermediate frequency pulse electrotherapy in the treatment of cervical spondylosis.Methods A total of 96 patients with cervical spondylosis from Xuchang People's Hospital between August 2021 and October 2022 were selected and divided into a combined group(48 cases) and a single treatment group(48 cases) according to a random number table.Patients in the single treatment group were treated with intermediate frequency pulse electrotherapy,while patients in the combined group were additionally treated with modified Qianghuo Shengshi decoction on the basis of the single treatment group.The clinical efficacy,time for symptoms to resolve(neck mobility restriction,neck stiffness,aversion to cold),numerical rating scale(NRS) for pain,cervical function scores [neck disability index(NDI),cervical range of motion(CROM)],levels of inflammatory factors [interleukin-6(IL-6),IL-1β,tumor necrosis factor-α(TNF-α)],and the incidence of adverse reactions were compared between the two groups.Results The combined group showed a higher total effective rate than the single treatment group.The time for symptoms to resolve,including neck mobility restriction,neck stiffness,and aversion to cold,was shorter in the combined group than that in the single treatment group.After one and two courses of treatment,the NRS scores were lower in the combined group compared to the single treatment group.After treatment,the NDI score was lower and the CROM score was higher in the combined group than that in the single treatment group.Additionally,the serum levels of IL-6,IL-1β,and TNF-α were lower in the combined group than those in the single treatment group,with statistically significant differences(P < 0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P > 0.05).Conclusion The treatment of cervical spondylosis with modified Qianghuo Shengshi decoction combined with intermediate frequen
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