血管活性药物在调节视网膜微循环中的作用  

The Role of Vasoactive Agents in Regulating Retinal Microcirculation

作　　者：高鹭 贺秋兰[2] 黄婵燕[2] 赵旭 GAO Lu;HE Qiulan;HUANG Chanyan;ZHAO Xu(Department of Ophthalmology,The First Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510120,China;Department of Anesthesiology,The First Afiliated Hospital,Sun Yat-sen University,Guangzhou,Guangdong 510080,China)

机构地区：[1]广州医科大学附属第一医院眼科,广东广州510120 [2]中山大学附属第一医院麻醉科,广东广州510080

出　　处：《今日药学》2024年第3期236-240,共5页Pharmacy Today

基　　金：广东省药学会科学研究基金(2022MZ01);广州医科大学科研能力提升计划(2302107XM)。

摘　　要：血管活性药物是一类可通过调控血管舒缩和心脏运动以调节血管中的血流运动,从而调节血压和微循环灌注压的药物,在围手术期和重症治疗领域广泛应用。尽管血管活性药物对微循环的重要性在近年得到越来越多的重视,但是不同血管活性药物对微循环的影响仍不明确,其中一个关键原因是缺乏有效的微循环监测手段。视网膜血管是唯一可以在活体上观察到的微循环血管,了解血管活性药物对视网膜微循环血流的影响可能为进一步探究微循环调节提供新的思路。本文针对血管活性药物在视网膜微循环中的调节作用进行了综述,以期为后续研究和临床实践提供参考依据。Vasoactive agents are a class of drugs that regulate vasomotion and cardiac activity to adjust blood flow,blood pressure and microcirculation perfusion pressure.They are widely used in the perioperative and critical care fields.Despite the increasing recognition of the importance of vasoactive agents in microcirculation in recent years,the specific effects of different vasoactive agents on microcirculation remain unclear,and a key reason for this is the lack of satisfactory microcirculation monitoring methods.Retinal vessels are the only microcirculatory vessels that can be observed in vivo,and understanding the effects of vasoactive agents on retinal microcirculation can provide new insights into the regulation of microcirculation.This article provided a review of the regulatory effects of vasoactive agents on retinal microcirculation,aiming to provide evidence for future research and clinical practice.

关 键 词：血管活性药物 视网膜 微循环 

分 类 号：R988.1[医药卫生—药品] R774[医药卫生—药学]