《女科百问》治疗产后病用药规律数据挖掘研究  

Research on Data Mining of Medication Rules for Treating Postpartum Diseases in Nv Ke Bai Wen

作　　者：刘冰玉 武权生[1] 黄灿灿 吕银鑫 曾燕 张扬[1,2] LIU Bingyu;WU Quansheng;HUANG Cancan;LYU Yinxin;ZENG Yan;ZHANG Yang(Gansu University of Traditional Chinese Medicine,Lanzhou 730030,China;Key Laboratory of Dunhuang Medical and Translational Education,Lanzhou 730030,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730030 [2]敦煌医学与转化教育部重点实验室,甘肃兰州730030

出　　处：《陕西中医药大学学报》2024年第3期94-98,共5页Journal of Shaanxi University of Chinese Medicine

基　　金：敦煌医学与转化教育部重点实验室2020年度专项课题(DHYX20-17)。

摘　　要：目的基于数据挖掘探讨《女科百问》治疗产后病的用药规律,总结齐仲甫产后病的学术思想。方法整理齐仲甫《女科百问》产后病的内服方剂,建立标准数据库,对产后药物进行频数统计、聚类分析及关联规则探索。结果《女科百问》中产后内服方剂共40首,涉及中药112味,总频次计340次。用药以甘草、人参、肉桂为主;性味多以辛、甘、温并用;归经以脾经为最,心、肺经次之。关联规则探索得到药物组合17对,其中以“甘草-芍药”“甘草-肉桂”“当归-肉桂”支持度最高。结论齐仲甫认为产后病的发生与脾胃密切相关,治疗核心思想是“壮后天以愈虚损,行气血以化瘀滞,调营卫以合阴阳”,并根据病情灵活用药,不拘泥于一方一法。Objective The purpose of this study is to explore the medication patterns of Nv Ke Bai Wen in the treatment of postpartum diseases based on data mining,and to summarize Qi Zhongfu's academic ideas on postpartum diseases.Methods Organize the internal medication formulas for postpartum diseases in QI Zhongfu's Nv Ke Bai Wen,establish a standard database,and conduct frequency statistics,cluster analysis,and association rule exploration on postpartum drugs.Results As a result,there were a total of 40 prescriptions for oral administration in Nv Ke Bai Wen,involving 112 traditional Chinese medicines,with a total frequency of 340 times.The main medications used are Licorice,Ginseng,and Cinnamon;It is often used in combination with spicy,sweet,and warm flavors;The spleen meridian is the most important meridian,followed by the heart and lung meridians.Exploring association rules resulted in 17 pairs of drug combinations,among which“Licorice-Peony”,“Licorice-Cinnamon”,and“Angelica sinensis-Cinnamon”had the highest support.Conclusion QI Zhongfu believes that the occurrence of postpartum diseases is closely related to the spleen and stomach.The core treatment idea is to“strengthen the postnatal environment to heal deficiency and damage,promote Qi and blood circulation to remove stasis,regulate the Ying and guard to combine Yin and Yang”,and flexibly use drugs according to the condition,without being bound by one prescription or method.

关 键 词：齐仲甫 女科百问 产后病 数据挖掘 用药规律 

分 类 号：R271.43[医药卫生—中医妇科学]