昆虫miRNA与抗药性关系研究进展  

Research progress on the relationship between insect miRNA and insecticide resistance

作　　者：陆靖 张宇峰 杜峰 谭文彬 LU Jing;ZHANG Yufeng;DU Feng;TAN Wenbin(College of Basic Medicine,Jining Medical University,Jining 272067,Shandong,China;College of Medical Engineering,Jining Medical University)

机构地区：[1]济宁医学院基础医学院,山东济宁272067 [2]济宁医学院医药工程学院

出　　处：《中国病原生物学杂志》2024年第5期607-609,613,共4页Journal of Pathogen Biology

基　　金：济宁医学院贺林院士新医学临床转化工作站科研基金项目(No.JYHL2018MS18);济宁医学院大学生创新训练计划项目(No.cx2019067);2022年大学生创新计划项目(No.cx2022092z)。

摘　　要：昆虫抗药性已成为危害公共卫生的严重问题,对其抗药性机制的研究日渐深入,而在转录后表达调控方面,miRNA扮演重要角色。本文从病媒昆虫的传播力,综合防治措施,miRNA的合成、作用方式、鉴定方法、表达水平检测,以及对昆虫抗性的人工干预研究等方面对抗药性机制中miRNA的作用进行综述,以期为昆虫抗药性防治总结凝练成果,开拓研究思路。Insect resistance to insecticides has become a serious public health problem,and the mechanism of insect resistance has been deeply studied.In this paper,the transmissibility of vector insects,integrated control measures,Mirna Synthesis,action mode,identification method,expression level detection,the role of miRNA in the mechanism of insect resistance was reviewed in order to summarize the condensed results and develop new research ideas.

关 键 词：昆虫 MIRNA 抗性机制 综述 

分 类 号：R184[医药卫生—流行病学]