胆道微生态在胆结石形成过程中的作用研究进展  

Advances in research on the role of biliary tract microecology in gallstone formation

作　　者：崔立阳 应丽娜 李瑞芳 孙艳 张振宇 张骏 Cui Liyang;Ying Lina;Li Ruifang;Sun Yan;Zhang Zhenyu;Zhang Jun(The Second Clinical Medical College,Zhejiang Chinese Medical University,Hangzhou 310053,Zhejiang Province,China;Department of Gastroenterology,Zhejiang Provincial People's Hospital(People's Hospital of Hangzhou Medical College),Hangzhou 310014,Zhejiang Province,China;Graduate School of Bengbu Medical University,Bengbu 233030,Anhui Province,China;Department of Gastroenterology,The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Traditional Chinese Medicine),Hangzhou 310003,Zhejiang Province,China)

机构地区：[1]浙江中医药大学第二临床医学院,杭州310053 [2]浙江省人民医院杭州医学院附属人民医院消化内科,杭州310014 [3]蚌埠医科大学研究生院,蚌埠233030 [4]浙江中医药大学附属第一医院浙江省中医院消化内科,杭州310003

出　　处：《中国基层医药》2024年第4期636-640,共5页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：胆结石是一种消化系统的常见病,其发病机制复杂多样,是遗传因素、环境因素、生活方式等诸多机制相互影响作用的结果。随着近年来分子生物学技术的广泛运用,胆道微生态环境在胆结石发病过程中的作用越来越受到重视。该文收集关于胆道微生态与胆结石关系的最新相关文献,总结胆道微生态和胆结石关系的最新研究进展。探讨胆道微生态本身及其在胆固醇结石和胆色素结石的形成过程中发挥的作用。Cholelithiasis,a prevalent disease of the digestive system,is characterized by its intricate and diverse mechanisms,which are influenced by a complex interplay of genetic,environmental,lifestyle,and other factors.Recently,with the widespread application of molecular biology techniques,the role of the biliary tract microecological environment in the pathogenesis of gallstones has garnered increasing attention.This review includes the most recent and pertinent literature on the association between biliary tract microecology and gallstones,summarizing the latest research advancements in this field.Furthermore,it delves into the role of the biliary tract microecology in the formation of both cholesterol and pigment gallstones.

关 键 词：胆结石 胆道疾病 机会致病菌感染 抗药性 危险因素 综述 

分 类 号：R575.62[医药卫生—消化系统]