蒿芩白虎汤加减治疗小儿流行性感冒的临床研究  

Clinical study of Haoqin Baihu decoction in thetreatment of pediatric influenza

作　　者：卢焯明 张刚 杜洪煊 LU Zhuoming;ZHANG Gang;DU Hongxuan(Department of Traditional Chinese Medicine Pediatrics,Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou,Guangdong,510623,China)

机构地区：[1]广州医科大学附属妇女儿童医疗中心中医儿科,广东广州510120

出　　处：《当代医学》2024年第4期138-142,共5页Contemporary Medicine

摘　　要：目的探究蒿芩白虎汤治疗小儿流行性感冒(流感)的临床疗效。方法选取2019年1月至2021年2月广州市妇女儿童医疗中心3个院区的122例流感患儿作为研究对象,根据治疗方法不同分为治疗组(n=60)与对照组(n=62)。治疗组给予蒿芩白虎汤加减治疗,对照组给予奥司他韦颗粒治疗,比较两组热峰、发热持续时间、症状体征改善情况及治愈率及甲型乙型流感病毒核酸阳性患儿症状、体征改善情况。结果两组热峰比较差异无统计学意义;治疗组发热持续时间短于对照组,差异有统计学意义(P<0.05)。治疗5d后,两组咳嗽、鼻塞或流涕、头痛、咽红或扁桃体红肿、眼结膜充血、腹泻或呕吐发生率均低于治疗前,治疗组咽痛、肌肉酸痛或乏力发生率均低于治疗前,差异有统计学意义(P<0.05),对照组治疗前后咽痛、肌肉酸痛或乏力发生率比较差异无统计学意义。治疗后,治疗组咳嗽生率低于对照组,差异有统计学意义(P<0.05),两组其他症状发生率比较差异无统计学意义。治疗组治愈率为61.7%,高于对照组的40.3%,差异有统计学意义(P<0.05)。两组甲型乙型流感病毒核酸阳性患儿间治疗前后各症状、体征比较差异均无有统计学意义。结论蒿芩白虎汤治疗小儿流感效果确切,可缩短流感患儿发热持续时间,改善患儿临床症状,具有较高的临床应用价值。Objective To study the clinical efficacy of Haoqin Baihu decoction in the treatment of children with influenza.Methods 122 chil-dren with influenza in 3 hospitals of Guangzhou Women and Children's Medical Center from January 2019 to February 2021 were selected as the study subjects,they were divided into the treatment group(n=60)and the control group(n=62)according to different treatment methods.The treat-ment group was treated with Haoqin Baihu decoction and the control group was treated with oseltamivir granules.The thermal peak,duration of fe-ver,improvement of symptoms and signs,the cure rate,and the improvement of symptoms and signs of influenza A and B virus nucleic acid positive children were compared between the two groups.Results There was no significant difference in thermal peak between the two groups;the duration of fever in the treatment group was shorter than that in the control group,the difference was statistically significant(P<0.05).After treatment,the in-cidences of cough,nasal congestion or runny nose,headache,red throat or tonsil,conjunctival hyperemia,diarrhea or vomiting in the two groups were lower than those before treatment,and the incidences of sore throat,muscle soreness or fatigue in the treatment group were lower than those be-fore treatment,and the differences were statistically significant(P<0.05),there was no significant difference in the incidence of sore throat,muscle soreness or fatigue before and after treatment in the control group;after treatment,the incidence of cough in the treatment group was lower than that in the control group,the difference was statistically significant(P<0.05),and there was no statistically significant difference in the incidence of other symptoms between the two groups.The cure rate in the treatment group was 61.7%,which was higher than 40.3%in the control group,and the differ-ence was statistically significant(P<0.05).There was no significant difference in symptoms and signs between the two groups of children with posi-tive influenza A and B virus n

关 键 词：蒿芩白虎汤 儿童 流行性感冒 奥司他韦颗粒 

分 类 号：R725.1[医药卫生—儿科]