超选择性肾动脉栓塞术对经皮肾镜碎石取石术肾出血患者止血和肾功能的影响  

Effect of superselective renal artery embolization on hemostasis and renal function in patients with percutaneous nephrolithotripsy renal hemorrhage

作　　者：彭辉 余俊 周薇 PENG Hui;YU Jun;ZHOU Wei(Department of Interventional Medicine,Fuzhou First People's Hospital,Fuzhou,Jiangxi,344000,China)

机构地区：[1]抚州市第一人民医院介入医学科,江西抚州344000

出　　处：《当代医学》2024年第3期99-102,共4页Contemporary Medicine

基　　金：抚州市指导性科技计划项目(抚科计字[2021]21号,第25项)。

摘　　要：目的探讨超选择性肾动脉栓塞术对经皮肾镜碎石取石术(PCNL)肾出血患者止血和肾功能的影响。方法选取2020年3月至2021年5月抚州市第一人民医院收治的60例PCNL肾出血患者作为研究对象,按照随机数字表法分为对照组与观察组,每组30例。对照组接受气囊导管压迫性止血治疗,观察组接受超选择性肾动脉栓塞术治疗。比较两组止血效果[出血量、血红蛋白(Hb)、血细胞比容(HCT)]、并发症发生情况及肾功能指标[血肌酐(SCr)、血尿素氮(BUN)]。结果观察组出血量少于对照组,差异有统计学意义(P<0.05);治疗后,两组Hb及观察组HCT均高于治疗前,且观察组Hb、HCT均高于对照组,差异有统计学意义(P<0.05)。两组并发症发生率比较差异无统计学意义。治疗后,两组血清SCr、BUN水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。结论超选择性肾动脉栓塞术治疗PCNL肾出血患者止血效果显著,可有效提升患者的肾功能,且不会增加并发症的发生风险,值得临床推广应用。Objective To explore the effect of superselective renal artery embolization on hemostasis and renal function in patients with percuta-neous nephrolithotripsy(PCNL)renal hemorrhage.Methods 60 patients with renal hemorrhage after PCNL were admitted to Fuzhou First People's Hospital from March 2020 to may 2021 were selected as the study subjects,and they were divided into control group and observation group by ran-dom number table method,with 30 cases in each group.The control group received compression hemostasis with balloon catheter,and the observa-tion group received superselective renal artery embolization.The hemostatic effects(bleeding volume,hemoglobin[Hb],hematocrit[HCT]),compli-cations and renal function indexes(blood creatinine[SCr]and blood urea nitrogen[BUN])were compared between the two groups.Results The amount of blood loss in the observation group was less than that in the control group,and the difference was statistically significant(P<0.05);after treatment,Hb of the two groups and HCT in observation group were higher than those before treatment,the Hb and HCT in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the inci-dence of complications between the two groups.After treatment,serum SCr and BUN levels of the two groups were lower than those before treatment,and the observation group was lower than the control group,and the differences were statistically significant(P<0.05).Conclusion Superselective renal artery embolization has remarkable hemostatic effect on patients with PCNL renal hemorrhage,can effectively improve the renal function of pa-tients,without increasing the risk of complications,and is worthy of clinical promotion and application.

关 键 词：经皮肾镜碎石取石术 超选择性 肾动脉栓塞术 止血效果 肾功能 

分 类 号：R699.2[医药卫生—泌尿科学]