人工肌腱/韧带生物材料研究进展  

Advances in biomaterials of artificial tendon/ligament

作　　者：杨冬逸 李刚 YANG Dongyi;LI Gang(College of Textile and Clothing Engineering,Soochow University,Suzhou 215000,Jiangsu,China;National Engineering Laboratory for Modern Silk,Soochow University,Suzhou 215123,Jiangsu,China;Nantong Textile&Silk Industrial Technology Research Institute,Nantong 226300,Jiangsu,China)

机构地区：[1]苏州大学纺织与服装工程学院,江苏苏州215000 [2]苏州大学现代丝绸国家工程实验室,江苏苏州215123 [3]南通纺织丝绸技术研究院,江苏南通226300

出　　处：《上海纺织科技》2024年第4期6-12,63,共8页Shanghai Textile Science & Technology

基　　金：国家重点研发计划(2021YFE0111100);科技部对发展中国家常规性科技援助项目(KY202201002);江苏省科技计划专项(BZ2022017);江苏省先进纺织工程技术中心创新项目(XJFZ/2021/7);中国纺织工业联合会“纺织之光”应用基础研究计划项目(J202002)。

摘　　要：随着人们预期寿命的延长和高强度运动的普及,肌腱/韧带(TL)损伤的频率也随之增加。由于其组织的特异性,受损肌腱和韧带的快速恢复对治疗极具挑战性。基于不同生物材料、制备技术、生物活性分子和细胞等在治疗修复TL损伤方面的最新进展,介绍了TL损伤与治疗的现状,回顾了天然生物聚合物和合成生物聚合物材料在TL组织修复中的应用,讨论了当前TL组织支架的制备技术和再生策略,以期为TL组织修复生物材料的开发提供参考。With increasing life expectancy and the popularity of high-intensity exercise,the frequency of tendon/ligament(TL)injuries has increased,and rapid recovery of damaged tendons and ligaments is challenging to treat due to their tissue specificity.Based on the latest progress of different biomaterials,preparation techniques,bioactive molecules and cells in the treatment and repair of TL damage,the status quo of TL damage and treatment is introduced,the application of natural biopolymer and synthetic biopolymer materials in TL tissue repair is reviewed,and the current preparation techniques and regeneration strategies of TL tissue scaffolds are discussed,in order to provide a new idea for the development of TL tissue repair biomaterials.

关 键 词：TL损伤 生物材料 聚合物 组织支架 制备技术 再生策略 

分 类 号：TS106.67[轻工技术与工程—纺织工程] R318.08[轻工技术与工程—纺织科学与工程]