ROS-induced metabolic reprogramming to one-carbon metabolism and S-adenosylmethionine-mediated epigenetic modification in IL-10-producing B cells for the resolution of pneumonia  

作　　者：Sujin Lee Tae Jin Kim 

机构地区：[1]Department of Immunology,Sungkyunkwan University School of Medicine,Suwon,16419,Republic of Korea

出　　处：《Cellular & Molecular Immunology》2024年第2期203-204,共2页中国免疫学杂志（英文版）

摘　　要：B cells have an essential immunoregulatory function,which is mediated by the secretion of IL-10 and TGFβand interaction with activated CD4^(+)T cells.This antibody-independent function of B cells contributes to ameliorating autoimmune diseases or infection-induced tissue damage.In this Cellular and Molecular Immunology issue,Fu et al.demonstrated that regulatory B(Breg)cells play a critical role in resolving Pseudomonas aeruginosa-induced pneumonia[1].

关 键 词：METABOLISM PNEUMONIA IMMUNOLOGY 

分 类 号：R392.2[医药卫生—免疫学] R563.1[医药卫生—基础医学]