Therapeutic Effect of Rhodopseudomonas palustris-Bioconverted Extract of Lycium barbarum on Rats with Lead Exposure  

作　　者：YANG Hong SUN Yi CHAI Shu Tong LIANG Yan Hui LIU Ya Ni YANG Guan E 

机构地区：[1]School of Pharmacy,Shanxi Medical University,Taiyuan 030001,Shanxi,China

出　　处：《Biomedical and Environmental Sciences》2024年第4期440-444,共5页生物医学与环境科学（英文版）

基　　金：sponsored by the Central Government Guides Local Scientific and Technological Development Fund Project(YDZX 20201400001443);Shanxi International Science and Technology Cooperation Project(201803D421065);National Natural Science Foundation of China(Grant No.30672621 and 81173473);Taiyuan City Science and Technology Project Special Talents Star Project(120247-08);Basic Research Project of Shanxi Province(202103021223241).

摘　　要：Lead is a ubiquitous pollutant and Pb pollution is a global public health problem.Lead has been reported to induce multiple adverse effects,including reproductive toxicity,neurotoxicity,carcinogenicity,nephrotoxicity,immunotoxicity,and hypertension[1].The traditional medical treatment available for Pb poisoning is chelation,which can save lives in individuals with very high blood Pb levels.The commonly used chelating agents include CaNa2EDTA and meso-2,3-dimercaptosuccinic acid.However,chelation therapy has strong short-term effects on the overall long-term management of Pb exposure.

关 键 词：converted CHELATION CHELATING 

分 类 号：R114[医药卫生—卫生毒理学]