基于态靶辨治理论诊疗慢性阻塞性肺疾病  

Research on diagnosis and treatment of chronic obstructive pulmonary disease based on the theory of state-target treatment based on syndrome differentiation

作　　者：王敏[1] 朱蔚[2] 王文洁 林轶群[4] 田传玺 王蕾[1] WANG Min;ZHU Wei;WANG Wenjie;LIN Yiqun;TIAN Chuanxi;WANG Lei(Guang'anmen Hospital,Chinese Academy of Chinese Medical Sciences,Beijing 100053,China;The 942nd Hospital of the People's Liberation Army Joint Logistic Support Force,Yinchuan 750000,China;Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010,China;South District of Guang'anmen Hospital,Chinese Academy of Chinese Medical Sciences,Beijing 102699,China;Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]中国中医科学院广安门医院,北京100055 [2]中国人民解放军联勤保障部队第九四二医院,银川750000 [3]首都医科大学北京中医医院,北京100010 [4]中国中医科学院广安门医院南区,北京102699 [5]北京中医药大学,北京100029

出　　处：《长春中医药大学学报》2024年第5期495-498,共4页Journal of Changchun University of Chinese Medicine

基　　金：国家自然科学基金面上项目(81473613)。

摘　　要：慢性阻塞性肺疾病是常见的呼吸系统气道慢性病,严重影响患者的生活质量。传统的中医辨证论治体系存在对疾病的发生发展规律认识不足,对检查化验指标改善欠佳的问题。仝小林院士经过多年的临床实践,提出“态靶辨治”的现代中医诊疗体系,并将其用于慢性疾病临床诊疗过程中。基于此,以“态靶辨治”理论为指导,结合临床经验与现代药理学研究成果,将慢性阻塞性肺疾病发病过程分为“痰、阻、瘀、衰”四态(四期),每态下进行分证,并结合治疗靶点,确定各阶段相应的靶方靶药,构建慢性阻塞性肺疾病的态靶辨治体系,为提高该病的中医治疗效果提供新的路径。Chronic obstructive pulmonary disease(COPD)is a common chronic respiratory disease,which seriously affects the quality of life of patients.The traditional Chinese medicine(TCM)treatment based on syndrome differentiation system has the problems of insufficient understanding of the occurrence and development regularity of diseases,and inadequate improvement of the examination and laboratory indicators.After years of clinical practice,Academician Tong Xiaolin puts forward a modern TCM diagnosis and treatment system of"state-target treatment based on syndrome differentiation",and applies it to the clinical diagnosis and treatment of chronic diseases.Based on this,under the guidance of the theory of"state-target treatment based on syndrome differentiation",combined with clinical experience and modern pharmacological research results,the pathogenesis of COPD is divided into four states(four stages),namely"phlegm,obstruction,blood stasis,and failure.For each state,syndrome differentiation is carried out.And combined with the treatment targets,the corresponding target prescription and target drug in each stage are determined,and the state-target treatment based on syndrome differentiation system of COPD is constructed,which provides a new path for improving the treatment effect of TCM.

关 键 词：慢性阻塞性肺疾病 态靶辨治 分期识态 靶方靶药 

分 类 号：R256.1[医药卫生—中医内科学]