胃癌患者行近端胃大部分切除术中应用不同袢氏吻合术的临床疗效分析  

Clinical Efficacy Analysis of Different Collaterals Anastomoses Applied in Proximal Gastric Majority Resection for Gastric Cancer Patients

作　　者：刘峰[1] 马丽敏 Liu Feng;Ma Limin(Department of Gastrointestinal Surgery,Heze Shanxian Center Hospital,Heze 274300,Shandong Province,China)

机构地区：[1]菏泽市单县中心医院胃肠外科,山东菏泽274300

出　　处：《中外医药研究》2024年第7期66-68,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:探讨在胃癌患者行近端胃大部分切除术中采用不同袢氏吻合术治疗的临床效果。方法:选择2019年7月—2022年7月于菏泽市单县中心医院拟行近端胃大部分切除术的胃癌患者126例作为研究对象,随机分为观察组(间置空肠吻合)与对照组(食管残胃端侧吻合),各63例。比较两组手术前后血清胃肠激素[胃泌素(GAS)、胃动素(MYL)、胆囊收缩素(CCK)、生长抑素(SS)]水平及术后6个月反流发生率、Visick分级、胃肠道症状评定量表(GSRS)评分。结果:术后6个月,观察组GAS、CCK水平均高于对照组,SS水平低于对照组,差异有统计学意义(P<0.05);两组MTL水平比较,差异无统计学意义(P>0.05)。观察组反流发生率低于对照组,差异有统计学意义(P=0.014)。观察组Visick分级优于对照组,差异有统计学意义(P<0.001)。观察组GSRS评分低于对照组,差异有统计学意义(P=0.049)。结论:对于胃癌患者,采用近端胃大部分切除术结合间置空肠吻合术,可有效降低胃反流发生率,减轻胃肠道症状,改善胃肠激素水平。Objective:To investigate the clinical effect of applying different collaterals'anastomosis in proximal gastric majority resection for gastric cancer patients.Methods:One hundred and twenty-six gastric cancer patients who were to undergo proximal gastric majority resection in Heze Shanxian Center Hospital from July 2019 to July 2022 were selected as the study subjects,and were randomly divided into the observation group(interstitial jejunal anastomosis)and the control group(esophageal remnant gastric telangiectasia anastomosis)with sixty-three cases in each group.Serum gastrointestinal hormone[gastrin(GAS),gastric motility(MYL),cholecystokinin(CCK),growth inhibitory hormone(SS)]levels before and after surgery and the incidence of reflux,Visick classification,and Gastrointestinal Symptom Rating Scale(GSRS)scores 6 months after surgery were compared between the two groups.Results:Six months after surgery,the levels of GAS and CCK in the observation group were higher than those in the control group,and the level of SS was lower than that in the control group,with a statistically significant difference(P<0.05);there was no statistically significant difference in the level of MTL between the two groups(P>0.05);and the incidence of reflux in the observation group was lower than that in the control group,with a statistically significant difference(P=0.014);the Visick grading of the observation group was better than that of the control group,and the difference was statistically significant(P<0.001);the GSRS score of the observation group was lower than that of the control group,and the difference was statistically significant(P=0.049).Conclusion:For patients with gastric cancer,the use of proximal gastric majority resection combined with interstitial jejunal anastomosis can effectively reduce the incidence of gastric reflux,alleviate gastrointestinal symptoms,and improve gastrointestinal hormone levels.

关 键 词：近端胃大部切除术 间置空肠吻合 食管残胃端侧吻合 反流 

分 类 号：R656.61[医药卫生—外科学]