有创-无创序贯机械通气治疗慢性阻塞性肺疾病合并呼吸衰竭患者的效果  

Effects of invasive-noninvasive sequential mechanical ventilation in treatment of patients with chronic obstructive pulmonary disease complicated with respiratory failure

作　　者：曾闪闪 ZENG Shanshan(Department of Respiratory and Critical Care Medicine of Wugang People’s Hospital,Pingdingshan 462500 Henan,China)

机构地区：[1]舞钢市人民医院呼吸与危重症医学科,河南平顶山462500

出　　处：《中国民康医学》2024年第8期29-32,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:探讨有创-无创序贯机械通气治疗慢性阻塞性肺疾病(COPD)合并呼吸衰竭患者的效果。方法:回顾性分析2022年6月至2023年6月该院收治的66例COPD合并呼吸衰竭患者的临床资料,按照机械通气方法的不同将其分为观察组和对照组各33例。对照组采取有创机械通气治疗,观察组采取有创-无创序贯机械通气治疗。比较两组总机械通气时间、有创机械通气时间、住院时间,治疗前后动脉血气指标[动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))、pH值]、心功能损伤指标[肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白I(cTnI)]水平,治疗2周内脱机成功率及并发症发生率。结果:治疗后,观察组总机械通气时间、有创机械通气时间和住院时间均短于对照组,差异有统计学意义(P<0.05);治疗后,观察组PaO_(2)水平、pH值均高于对照组,PaCO_(2)水平低于对照组,差异有统计学意义(P<0.05);观察组脱机成功率为96.97%(32/33),高于对照组的75.76%(25/33),并发症发生率为6.06%(2/33),低于对照组的24.24%(8/33),差异均有统计学意义(P<0.05)。结论:有创-无创序贯机械通气用于COPD合并呼吸衰竭患者中能够缩短机械通气时间和住院时间,改善患者血气指标和心功能,提高脱机成功率,并降低并发症发生率,效果优于常规有创机械通气治疗。Objective:To investigate effects of invasive-noninvasive sequential mechanical ventilation in treatment of patients with chronic obstructive pulmonary disease(COPD)complicated with respiratory failure.Methods:The clinical data of 66 patients with COPD complicated with respiratory failure admitted to this hospital from June 2022 to June 2023 were retrospectively analyzed.According to the different methods of mechanical ventilation,they were divided into observation group and control group,33 cases in each group.The control group was treated with invasive mechanical ventilation,while the observation group was treated with invasive-noninvasive sequential mechanical ventilation.The total mechanical ventilation time,the invasive mechanical ventilation time,the hospitalization time,the levels of arterial blood gas indexes[arterial partial pressure of oxygen(PaO_(2)),arterial partial pressure of carbon dioxide(PaCO_(2)),pH value]and cardiac function injury indexes[creatine kinase isoenzyme(CK-MB),cardiac troponin I(cTnI)]before and after treatment,the offline success rate within 2 weeks of treatment,and the incidence of complications were compared between the two groups.Results:After the treatment,the total mechanical ventilation time,the invasive mechanical ventilation time and the hospitalization time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the PaO_(2)level and pH value of the observation group were higher than those of the control group,the PaCO_(2)level was lower than that of the control group,and the differences were statistically significant(P<0.05).Further,the offline success rate in the observation group was 96.97%(32/33),which was higher than 75.76%(25/33)in the control group;the incidence of complications was 6.06%(2/33),which was lower than 24.24%(8/33)of the control group;and the differences were statistically significant(P<0.05).Conclusions:Invasive-noninvasive sequential mechanical ventilation for t

关 键 词：慢性阻塞性肺疾病 呼吸衰竭 有创-无创 序贯机械通气 脱机成功率 疗效 

分 类 号：R563[医药卫生—呼吸系统]