非高密度脂蛋白胆固醇与2型糖尿病大血管病变相关性的研究进展  

Research Progress on the Correlation between Non-high-density Lipoprotein Cholesterol and Macrovascular Disease in Type 2 Diabetes Mellitus

作　　者：韦榕艳 WEI Rongyan(The People's Hospital of Guangxi Zhuang Autonomous Region,Nanning 530022,China)

机构地区：[1]广西壮族自治区人民医院(广西医学科学院),广西南宁530022

出　　处：《中外医学研究》2024年第11期160-163,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：糖尿病不仅需要关注,同时其导致的大血管病变更是全球健康威胁的主要原因之一。随着糖尿病大血管并发症发生率的增加,急需新的指标及策略来预防疾病进展。血脂异常增加了大血管并发症的可能性,包括冠心病、中风或外周血管疾病。本篇综述旨在全面分析非高密度脂蛋白胆固醇(non-HDL-C)与大血管病变的相关性,进一步论证non-HDL-C是否可替代低密度脂蛋白胆固醇(LDL-C)作为未来潜在的治疗靶点。The diabetes not only requires attention,but also the alteration of large vascular diseases caused by it is one of the major causes of global health threats.With the increasing incidence of diabetic macrovascular complications,new indicators and strategies are urgently needed to prevent disease progression.Dyslipidemia increases the likelihood of major vascular complications,including coronary heart disease,stroke,or peripheral vascular disease.This review aims to comprehensively analyze the association between non-highdensity lipoprotein cholesterol(non-HDL-C)and macrovascular disease,and further demonstrate whether non-HDL-C can replace lowdensity lipoprotein cholesterol(LDL-C)as a potential therapeutic target in the future.

关 键 词：非高密度脂蛋白胆固醇 2型糖尿病 大血管病变 

分 类 号：R587.2[医药卫生—内分泌]