化痰祛瘀法在急性脑梗死血管新生中的研究进展  

Research Progress of the Method of Resolving Phlegm and Removing Blood Stasis in Angiogenesis of Acute Cerebral Infarction

作　　者：苏滢滢 陈甦 杨洋 SU Yingying;CHEN Su;YANG Yang(Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China)

机构地区：[1]福建中医药大学,福建福州350122 [2]福建中医药大学附属人民医院

出　　处：《中外医学研究》2024年第12期179-184,共6页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：急性脑梗死是发病率和患病率持续升高的急性脑血管病。血管新生是急性脑梗死的潜在防御机制,治疗性血管新生是基于急性脑梗死血管新生机制一种新的选择,急性脑梗死发生后可诱导生成大量的血管调控因子并且牵动多种信号通路。祖国医学和现代临床研究证明,痰、瘀是致病的关键之因,化痰祛瘀则新血得生,新血生以助痰瘀尽。化痰祛瘀法可作用于血管新生信号通路及调节因子从而诱导血管新生,具有良好的临床价值和不良反应少的优点。本文对化痰祛瘀法在急性脑梗死血管新生中的研究进行综述,以期为中医药治疗急性脑梗死提供借鉴。Acute cerebral infarction is an acute cerebrovascular disease with an increasing incidence rate and prevalence.Angiogenesis is a potential defense mechanism for acute cerebral infarction,and therapeutic angiogenesis is a new choice based on the angiogenic mechanism of acute cerebral infarction.After the occurrence of acute cerebral infarction,it can induce the generation of a large number of vascular regulatory factors and affect multiple signaling pathways.Traditional Chinese medicine and modern clinical research have proven that phlegm and blood stasis are the key causes of disease.Resolving phlegm and removing blood stasis leads to the generation of new blood.New blood is generated to assist in the exhaustion of phlegm and blood stasis.The method of resolving phlegm and removing blood stasis can act on the angiogenesis signaling pathway and related regulatory factors to induce angiogenesis,which has good clinical value and the advantage of fewer adverse reactions.This article reviews the study of eliminating phlegm and removing blood stasis in the angiogenesis of acute cerebral infarction,in order to provide reference for the treatment of acute cerebral infarction with traditional Chinese medicine.

关 键 词：化痰祛瘀法 急性脑梗死 血管新生 

分 类 号：R277.7[医药卫生—中医学]