荔枝核总皂苷药理活性的研究进展  

Research progress in pharmacological activities of total saponins from litchi seeds

作　　者：黄映捷 卢玉翠 盘家萍 赵立春[2,3] HUANG Yingjie;LU Yucui;PAN Jiaping;ZHAO Lichun(Department of Pharmacy,Guangxi University of Chinese Medicine,Nanning 530200,China;Guangxi University of Chinese Medicine Scientific Research Center,Nanning 530200,China;Guangxi Zhuang Yao Medicine Center of Engineering and Technology,Nanning 530200,China)

机构地区：[1]广西中医药大学药学院,南宁530200 [2]广西中医药大学科学实验中心,南宁530200 [3]广西壮瑶药工程技术研究中心,南宁530200

出　　处：《西北药学杂志》2024年第3期235-241,共7页Northwest Pharmaceutical Journal

基　　金：国家自然科学基金项目(编号:82160775);国家青年岐黄学者项目(编号:2020-7);广西中医药大学研究生教育创新计划项目(编号:YCSY2022009)。

摘　　要：目的了解并总结荔枝核总皂苷的药理活性研究进展。方法通过检索国内外相关文献,对荔枝核总皂苷的药理作用进行归纳总结。结果荔枝核总皂苷具有抗炎、降血糖、抗氧化、抗阿尔茨海默病等多种生物活性及药理作用。结论荔枝核总皂苷的药理作用体现在多个方面,但针对这些作用机制的研究还较少,后期应加强其在临床应用方面的相关研究。Objective To understand and summarize the pharmacological activity studies of total saponins of litchi seeds.Methods By searching the relevant literatures at domestic and abroad,the pharmacological effects of total saponins from litchi seeds were summarized.Results The total saponins from litchi seeds have many biological activities and pharmacological effects,such as antiinflammatory,hypoglycemic,antioxidant and anti-Alzheimer’s disease(AD).Conclusion The pharmacological effects of the total saponins from litchi seeds are reflected in many aspects,but the research on the mechanism of action is not enough,and the related research on its clinical application should be strengthened in the later stage.

关 键 词：荔枝核 总皂苷 药理活性 机制研究 

分 类 号：R285[医药卫生—中药学]