采用MSCT灌注成像检查评估周围型非小细胞肺癌分化程度的可行性分析  

Feasibility of MSCT Perfusion Imaging in Assessing the Degree of Differentiation of Peripheral Non-Small Cell Lung Cancer

作　　者：江叶[1] 汪祝莎[1] 孙韬[1] 何洪林 JIANG Ye;WANG Zhu-Sha;SUN Tao;HE Hong-lin(Department of medical imaging,Central South Hospital,Wuhan University 430071,Hubei Province,China;Department of Radiology,central theater General Hospital of PLA,Wuhan 430070,Hubei Province,China)

机构地区：[1]武汉大学中南医院医学影像科,湖北武汉430071 [2]中国人民解放军中部战区总医院放射影像科,湖北武汉430070

出　　处：《中国CT和MRI杂志》2024年第5期77-78,共2页Chinese Journal of CT and MRI

摘　　要：目的分析多层螺旋CT(MSCT)灌注成像检查评估周围型非小细胞肺癌(NSCLC)分化程度的可行性。方法选取本院2017年7月至2018年10月本院收治确诊的52例周围型NSCLC患者作为研究对象,比较不同分化级别患者的MSCT灌注成像参数;分析灌注参数与分化程度的相关性。结果高分化、中分化周围型NSCLC患者BF、BV、PS、MTT及PH数值均高于低分化周围型NSCLC,以高分化周围型NSCLC的BF、BV、PS、MTT及PH数值最高。各个灌注参数值,其中高分化、中分化周围型NSCLC的BF、PH与低分化周围型NSCLC比较差异显著(P<0.05),三者BV、PS及MTT数值比较,均为明显差异(P>0.05)。周围型NSCLC患者灌注参数BF、PH与其分化程度成负相关,且相关性显著(P<0.05)。结论MSCT灌注成像检查可有效反映周围型NSCLC的分化程度,其灌注参数中BF、PH对评估其分化程度有一定帮助,与周围型NSCLC分化程度具有一定相关性。Objective To analyze the feasibility of multi-slice spiral CT(MSCT)perfusion imaging in assessing the degree of differentiation of peripheral non-small cell lung cancer(NSCLC).Method 52 patients with peripheral NSCLC admitted and diagnosed in our hospital from July 2017 to October 2018 were selected as research objects,and the MSCT perfusion imaging parameters of patients in different differentiation levels were compared.The correlation between perfusion parameters and the degree of differentiation was analyzed.Results The values of BF,BV,PS,MTT,and PH of patients with highly differentiated and moderately differentiated peripheral NSCLC were higher than those of patients with poorly differentiated peripheral NSCLC,and the values of BF,BV,PS,MTT,and PH of patients with highly differentiated peripheral NSCLC were the highest.There was a significant difference between the highly differentiated,moderately differentiated peripheral NSCLC and the poorly differentiated peripheral NSCLC in BF and PH(P<0.05).There were significant differences in BV,PS and MTT values among the them(P>0.05).Perfusion parameters BF and PH in peripheral NSCLC patients were negatively correlated with their differentiation degree,and the correlation was significant(P<0.05).Conclusion MSCT perfusion imaging can effectively reflect the degree of differentiation of peripheral NSCLC.The BF and PH in its perfusion parameters are helpful to evaluate the degree of differentiation and have some correlation with the degree of differentiation of peripheral NSCLC.

关 键 词：多层螺旋CT 灌注成像 周围型非小细胞肺癌 分化程度 

分 类 号：R445.3[医药卫生—影像医学与核医学]