广东省湛江市人类嗜T淋巴细胞病毒感染情况分析  

Analysis of Human T-lymphotropic Virus Infection in Zhanjiang City of Guangdong

作　　者：周娇玲 申爱君 单振刚 陈嘉莉 ZHOU Jiaoling;SHEN Aijun;SHAN Zhengang;CHEN Jiali(Laboratory Department,Zhanjiang City Central Blood Station,Zhanjiang,Guangdong 524000;Clinical Transfusion Research Institute,Guangzhou Blood Center,Guangzhou,Guangdong 510095)

机构地区：[1]湛江市中心血站检验科,广东湛江524000 [2]广州市血液中心临床输血研究所,广东广州510095

出　　处：《智慧健康》2024年第3期30-32,共3页Smart Healthcare

摘　　要：目的 了解人类嗜T淋巴细胞病毒(HTLV)在湛江市献血人群中的感染情况。方法 采用酶联免疫双抗原夹心法(ELISA)检测取消互助献血前2016年3月—2018年2月献血人群的标本113304份和取消互助献血后2018年3—12月献血人群的标本36473份。ELISA阳性的标本送到广州市血液中心进行化学发光法检测和PCR确证试验,PCR确证阳性的视为HTLV感染。结果 113304份标本中酶免阳性77份,其中化学发光阳性17份,PCR确证阳性7份;36473份标本中酶免阳性16份,其中化学发光阳性3份,PCR确证阳性1份;感染率分别为0.062‰和0.027‰,总感染率为0.053‰。8位感染者均来自广东湛江市。结论 湛江市献血人群HTLV有低流行分布。Objective To understand infection status of human T-lymphotropic virus(HTLV) of blood donors in Zhanjiang City.Methods The paper detected 113304 samples of blood donors from March 1,2016 to February 28,2018 before cancellation of mutual aid blood donation and 36473 samples of blood donors from March 1,2018 to December 31,2018 after cancellation of mutual aid blood donation with enzyme-linked immunosorbent assay(ELISA).ELISA positive samples were delivered to Guangzhou Blood Center for chemiluminescence detection and PCR confirmation testing.Results There were 77 positive for enzyme immunoassay among 113 304 specimens,including 17 positive for chemiluminescence and 7 positive for PCR.Out of 36473 specimens,16 were positive for enzyme immunoassay,including 3 positive for chemiluminescence and 1 positive for PCR.Positive rate of HTLV was 0.062 ‰ and 0.027‰ respectively.8 cases confirmed positive for HTLV were all from Zhanjiang City of Guangdong.Conclusion There is low prevalence of HTLV among blood donors in Zhanjiang City.

关 键 词：人类嗜T淋巴细胞病毒 献血人群 流行分布 

分 类 号：R446.6[医药卫生—诊断学]