非那雄胺联合经尿道前列腺等离子切除术治疗前列腺增生患者的临床效果  

Clinical Effect of Finasteride Combined with Transurethral Plasma Resection of Prostate in Treatment of Patients with Benign Prostatic Hyperplasia

作　　者：王纯才 WANG Chuncai(Department of Urology,Fengxian County People's Hospital,Fengxian,Jiangsu 221700)

机构地区：[1]丰县人民医院泌尿外科,江苏丰县221700

出　　处：《智慧健康》2024年第3期111-114,共4页Smart Healthcare

摘　　要：目的 探究对前列腺增生患者行非那雄胺联合经尿道前列腺等离子切除术治疗的效果。方法 选取2020年6月—2023年3月本院收治的86例前列腺增生患者为研究对象,并按随机分组法分为对照组和观察组,每组43例。对照组行前列腺等离子切除术治疗+口服盐酸坦索罗辛缓释胶囊+口服5mg/片非那雄胺片,观察组行前列腺等离子切除术治疗+口服盐酸坦索罗辛缓释胶囊+口服10mg/片非那雄胺;对比两组I-PSS评分、生活质量、下尿路症状、手术及临床指标、不良反应情况。结果 治疗前两组I-PSS评分对比无差异(P>0.05),平均下尿路症状严重程度达到中度;治疗后观察组I-PSS评分低于对照组(P<0.05),平均下尿路症状严重程度达到轻度,而对照组依然为中度。治疗后观察组生活质量评分高于对照组(P<0.05)。观察组术中出血量、手术时间、术中冲洗液量均低/短于对照组(P<0.05);两组切除前列腺重量无差异(P>0.05)。观察组术后尿管拔除时间短于对照组,最大尿流率高于对照组(P<0.05)。观察组不良反应发生率较对照组更低(P<0.05)。结论 前列腺增生患者术前口服10mg/片非那雄胺,再行前列腺等离子切除术治疗,能缓解患者临床症状,提高其生活质量,降低术后不良反应。Objective To explore effect of finasteride patients combined with transurethral plasma resection on prostate with benign prostatic hyperplasia.Methods The paper reviewed and chose data of 86 patients with benign prostatic hyperplasia admitted to our hospital from June 2020to March 2023.43 cases in control group were treated with prostate plasma resection,oral sustainedrelease capsules of tamsulosin hydrochloride,and oral administration of 5mg/tablet of finasteride tablets;43 cases in observation group with prostate plasma resection,oral administration of tamsulosin hydrochloride sustained-release capsules,and oral administration of 10mg/tablet of finasteride.I-PSS scores,life quality,lower urinary tract symptoms,surgical and clinical indicators,and adverse reactions were compared between two groups.Results There was no difference in I-PSS scores between two groups before treatment(P>0.05),and average severity of lower urinary tract symptoms reached moderate.After treatment,I-PSS scores of observation group were lower than control group(P<0.05),and average severity of lower urinary tract symptoms reached mild,while control group remained moderate.Life quality scores of observation group after treatment were higher than control group(P<0.05).in traoperative bleeding volume,surgical time,and intraoperative flushing fluid volume in observation group was lower/shorter than control group(P<0.05).There was no difference in weight of excised prostate between two groups(P>0.05).Observation group had shorter postoperative catheter removal time than control group,and maximum urine flow rate was higher than control group(P<0.05).in cidence of adverse reactions in observation group was lower than control group(P<0.05).Conclusion Preoperative oral administration of 10mg/tablet of finasteride followed by Plasma prostatectomy can alleviate clinical symptoms,improve life quality,and reduce postoperative adverse reactions of patients with benign prostatic hyperplasia.

关 键 词：前列腺增生 前列腺等离子切除术 非那雄胺 

分 类 号：R699.8[医药卫生—泌尿科学]