苯磺酸瑞马唑仑复合静脉麻醉在宫颈环形电切术中的临床应用  

Clinical Application of Remazolam Besylate Combined with in travenous Anesthesia in Cervical Circular Resection Surgery

作　　者：谢月峰 XIE Yuefeng(Department of Anesthesiology,Taizhou City the Fourth People's Hospital,Taizhou,Jiangsu,225300)

机构地区：[1]泰州市第四人民医院麻醉科,江苏泰州225300

出　　处：《智慧健康》2024年第3期193-196,共4页Smart Healthcare

摘　　要：目的 探究在宫颈环形电切术中应用苯磺酸瑞马唑仑复合静脉麻醉的效果。方法 本次试验选取本院在2022年6月—2023年5月收治的60例行宫颈环形电切术患者,并将其作为数据分析对象,分组时按麻醉方案不同共分为对照和观察两组,每组30例。对照组实施舒芬太尼加丙泊酚方式,观察组在对照组基础上实施苯磺酸瑞马唑仑复合静脉麻醉,比较两组临床相关指标,心率(HR)、平均动脉压(MAP),苏醒质量,不良反应。结果 两组对比临床相关指标,观察组术中失血量、术中输液量与对照组差异无统计学意义(P>0.05),丙泊酚用量少于对照组,差异显著有统计学意义(P<0.05)。两组HR、MAP均呈现先降低后上升趋势,对比于对照组,观察组HR各时间点数值虽偏高,差异无统计学意义(P>0.05);两组MAP各时间点数值比较,观察组较高,差异显著有统计学意义(P<0.05)。两组对比苏醒质量,观察组各时间点改良警觉/镇静(MOAA/S)评分均高于对照组,差异显著有统计学意义(P<0.05)。两组对比不良反应,观察组明显低于对照组,差异显著有统计学意义(P<0.05)。结论 在对行宫颈环形电切术患者麻醉时,给予苯磺酸瑞马唑仑复合静脉麻醉,效果较为显著,在临床麻醉方案中值得大范围推广与实施。Objective To explore effect of remazolam besylate combined with intravenous anesthesia in cervical circular resection surgery.Methods The paper chose 60 patients with cervical circular resection in our hospital from June 2022 to May 2023 as analysis subjects,and divided them into two groups based on different anesthesia plans:control group and observation group,with 30 cases in each group.Control group was treated with sufentanil combined propofol,while observation group with remimazolam besylate combined intravenous anesthesia on the basis of control group.Clinical related indicators were compared between two groups:including heart rate(HR) and mean arterial pressure(MAP),awakening quality,adverse reactions.Results Clinically relevant indicators comparison showed,observation group had no significant difference in intraoperative blood loss(12.35±4.68) ml and intraoperative infusion volume(512.02±70.64) ml compared with control group(P> 0.05),while dosage of propofol(70.28±10.58) mg was less than control group,with significant difference(P<0.05).Both groups of HR and MAP showed trend of first decreasing and then increasing.Observation group had higher HR time points than control group,difference was not significant(P>0.05).Comparison of MAP values at different time points between two groups showed,observation group had higher value,with significant difference(P<0.05).Awakening quality comparison between two groups showed,MOAA/S scores in observation group were significantly higher than control group at all time points(P< 0.05).Adverse reactions in observation group were significantly lower than control group,with significant difference(P< 0.05).Conclusion During anesthesia of patients with cervical circular electrosurgical resection,combination of remimazolam besylate and intravenous anesthesia can achieve significant effect,which is worthy of promotion and application on a large scale in clinical anesthesia plans.

关 键 词：苯磺酸瑞马唑仑 复合静脉麻醉 宫颈环形电切术 丙泊酚 

分 类 号：R614[医药卫生—麻醉学]