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作 者:谭小娇 TAN Xiaojiao(Pingguo People's Hospital,Baise,Guangxi 531400)
出 处:《智慧健康》2024年第5期105-108,共4页Smart Healthcare
摘 要:目的 本研究采用心肌酶谱联合肌钙蛋白检测,为甲状腺功能减退症患者检查提供更准确的依据,并对心肌酶谱联合肌钙蛋白检测效果进行分析。方法 抽取本院2021年8月—2022年10月收治的68例健康体检人员与68例甲状腺功能减退症确诊患者。将健康体检人员设置为对照组,甲状腺功能减退症确诊患者设置为观察组。所有受试者均进行心肌酶谱、肌钙蛋白检测。比较两组心肌酶谱及肌钙蛋白相关指标、心肌酶谱与肌钙蛋白诊断情况及诊断效能。结果 观察组心肌酶谱、肌钙蛋白相关指标均显著高于对照组(P<0.05);将心肌酶谱、肌钙蛋白联合检测结果进行统计分析,可见心肌酶检测阳性53例,阴性83例;肌钙蛋白检测阳性43例,阴性93例;联合检测阳性65例,阴性71例。其中心肌酶谱的灵敏度为67.65%、特异性为89.71%、阳性预测值为86.79%、阴性预测值为73.49%;肌钙蛋白的灵敏度为55.88%、特异性为92.65%、阳性预测值为88.37%、阴性预测值为67.74%;联合检测的灵敏度为92.65%、特异性为97.06%、阳性预测值为96.92%、阴性预测值为92.95%。结论 采用心肌酶谱联合肌钙蛋白诊断甲状腺功能减退症患者在临床中取得显著效果,较单独采用某一项检验更具有临床价值。Objective In this study,myocardial enzymology combined with troponin detection was used to provide a more accurate basis for the examination of patients with hypothyroidism,and the effect of myocardial enzymology combined with troponin detection was analyzed.Methods 68healthy physical examiners and 68 patients with hypothyroidism diagnosed in our hospital from August 2021 to October 2022 were selected.The healthy physical examiners were set as control group,and the patients with confirmed hypothyroidism were set as observation group.Myocardial enzyme profile and troponin were detected in all subjects.Myocardial enzyme profile and troponin related indexes,diagnostic status and diagnostic efficacy of myocardial enzyme profile and troponin were compared between the two groups.Results Myocardial enzyme spectrum and troponin related indexes in observation group were significantly higher than those in control group(P< 0.05).The results of the combined detection of myocardial enzyme spectrum and troponin were statistically analyzed.53 cases were positive and 83 cases were negative.There were 43 positive and 93 negative troponin tests.The combined test was positive in 65 cases and negative in 71 cases.The sensitivity,specificity,positive predictive value and negative predictive value were 67.65%,89.71%,86.79% and 73.49%respectively.The sensitivity,specificity,positive predictive value and negative predictive value of troponin were 55.88%,92.65%,88.37% and 67.74% respectively.The sensitivity,specificity,positive predictive value and negative predictive value of combined detection were 92.65%,97.06%,96.92%and 92.95%.Conclusion The combination of myocardial enzymology and troponin in the diagnosis of hypothyroidism has achieved remarkable results in clinic,and is more valuable than any single test.
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