2020—2022年贵州省新生儿疾病筛查可疑阳性病例召回情况及其原因分析  

Recall of suspected positive cases of neonatal disease screening in Guizhou Province from 2020 to 2022 and analysis of their causes

作　　者：张铸业 尹亚茹 张莎莎 张玲 Zhang Zhuye;Yin Yaru;Zhang Shasha;Zhang Ling(Guizhou New Screening Center,Guiyang 550001,Guizhou,China)

机构地区：[1]贵州省妇幼保健院省新生儿疾病筛查中心,贵州贵阳550001

出　　处：《贵州医药》2024年第5期679-682,共4页Guizhou Medical Journal

基　　金：贵州省卫生健康委科学技术基金项目(编号:gzwkj2021-396)。

摘　　要：目的通过回顾性分析2020—2022年贵州省新生儿疾病筛查中心(简称新筛中心)可疑阳性召回情况,探索适合本地区的新生儿可疑阳性召回模式。方法以2020—2022年的贵州省新筛中心CH和PKU两病可疑阳性召回情况进行分析,以所辖区域的新生儿为研究对象,筛查结果阳性者及时召回,进行复查确诊;采用χ2检验进行统计描述。结果2020—2022年贵州省新筛中心共筛查532283例,平均筛查率为95.37%,CH初筛阳性数10861例,召回9669例,确诊188例;PKU初筛阳性数3156,召回2788例,确诊14例。CH和PKU在不同地区间的初筛阳性召回率均差异有统计学意义(P<0.05),不同病种之间差异无统计学意义(P>0.05)。结论贵州省新生儿疾病筛查中心筛查率逐年升高,但随着筛查病种的增加,初筛可疑阳性召回率呈下降趋势,应加强各级新筛管理机构可疑阳性召回管理,不断探索灵活的、人性化的召回模式,有效提高筛查可疑阳性召回率。Objective To retrospectively analyze the recall of suspicious positive newborns in Guizhou Neonatal Disease Screening Center from 2020 to 2022,and to explore the appropriate recall management mode for the region.Methods The recall of suspected positive cases of CH and PKU in Guizhou Neonatal Disease Screening Center from 2020 to 2022 was analyzed.The newborns with positive screening results were recalled in time for reconfirmation.χ2test was used for statistical description.Results From 2020 to 2022,532283 cases were screened by the new screening center in Guizhou Province,with an average screening rate of 95.37%.Among the 10861 positive cases for CH,9669 cases were recalled,and among the 3156 positive cases for PKU,2788 cases were recalled.There were significant differences in the recall rates of CH and PKU among different regions(P<0.05),but there was no significant difference among different diseases(P>0.05).Conclusions The screening rate of newborn disease screening center in Guizhou Province increased year by year,but with the increase of screening diseases,the recall rate of suspicious positive results in the initial screening showed a downward trend.It is necessary to strengthen the recall management of suspicious positive results in new screening management institutions at all levels,and explore flexible and humanized recall mode to effectively improve the recall rate of suspicious positive results in screening.

关 键 词：新生儿筛查 贵州地区 可疑阳性召回 

分 类 号：R272.1[医药卫生—中医儿科学]