45~65岁固定献血者献血后肝肾功能及血脂、血糖水平分析  

Liver and renal function,blood lipids,and blood glucose after blood donation in long-term blood donors aged 45-65 years

作　　者：刘晓华 许雷 白雪莲 逄淑涛 LIU Xiaohua;XU Lei;BAI Xuelian;PANG Shutao(Qingdao Blood Center,Qingdao 266073,China)

机构地区：[1]青岛市中心血站,山东青岛266073

出　　处：《精准医学杂志》2024年第2期167-169,174,共4页Journal of Precision Medicine

基　　金：青岛市中心血站项目(2017-xz07)。

摘　　要：目的了解45~65岁固定献血者献血后3个月的肝肾功能及血脂、血糖水平,探讨超献血年龄献血者继续献血的可能性。方法选择2016年9—12月于我站献血的固定献血者,按年龄分为45~49岁组(A组)、50~54岁组(B组)、55~59岁组(C组)和60~65岁组(D组),于最近一次献血后3个月检测各组献血者的肝肾功能、血糖及血脂水平,并进行比较。结果与D组献血者比较,A、B、C组献血者献血后3个月血清低密度脂蛋白胆固醇(LDL-C)水平差异显著(t=2.45~4.61,P<0.05),四组献血者献血后3个月肝肾功能和血糖水平差异无显著性(P>0.05)。结论45~59岁的固定献血者献血后3个月肝肾功能、血脂、血糖各指标稳定,长期献血不会影响上述指标。60~65岁献血者终止献血后LDL-C水平偏高,其他指标稳定,可以考虑成为潜在献血者。Objective To investigate the liver and renal function,blood lipids,and blood glucose at 3 months after blood donation in long-term blood donors aged 45-65 years,as well as the possibility of continuing to donate blood after exceeding the age for blood donation.Methods The long-term blood donors who donated blood at our station from September to December 2016 were selected,and according to the age,they were divided into group A(45-49 years of age),group B(50-54 years of age),group C(55-59 years of age),and group D(60-65 years of age).Liver and renal function,blood glucose,and blood lipid levels were measured at 3 months after the most recent blood donation and were compared between groups.Results There was a significant difference in the serum level of low-density lipoprotein cholesterol(LDL-C)at 3 months after blood donation between groups A/B/C and group D(t=2.45-4.61,P<0.05),while there were no significant differences between the four groups in liver and renal function and blood glucose at 3 months after blood donation(P>0.05).Conclusion The long-term blood donors,aged 45-59 years,tend to have stable liver and renal function,blood lipids,and blood glucose at 3 months after blood donation,and long-term blood donation does not affect the above indicators.The blood donors aged 60-65 years have a higher level of LDL-C after blood donation,with other indicators remaining stable,and therefore,they may be considered as potential blood donors.

关 键 词：供血者 血糖 脂类 血液化学分析 肝功能试验 肾功能试验 中年人 

分 类 号：R446.11[医药卫生—诊断学] R193.3[医药卫生—临床医学]