甲状旁腺原位保留与即刻主动自体移植术后甲状旁腺功能对比分析  

Comparative analysis of parathyroid function between in situ preservation and immediate active autotransplantation of parathyroid glands

作　　者：崔艳钊 CUI Yan-zhao(Beijing Huopu Hospital,Beijing 102200,China)

机构地区：[1]北京霍普医院,102200

出　　处：《中国实用医药》2024年第8期67-70,共4页China Practical Medicine

摘　　要：目的 针对甲状旁腺原位保留与甲状旁腺即刻主动自体移植术后甲状旁腺功能进行回顾性分析,为临床治疗提供参考。方法 回顾性分析636例首次进行甲状腺癌手术治疗患者的临床资料,根据甲状旁腺处理方式不同分为对照组(甲状旁腺原位保留的患者, 517例)和研究组(接受甲状旁腺即刻主动自体移植术的患者, 119例)。比较两组患者手术前后血清甲状旁腺激素、血钙水平。结果 对照组术前、术后第1天、术后第3天甲状旁腺激素分别为(58.82±3.47)、(32.48±3.76)、(46.86±3.65)pg/ml,血钙分别为(2.26±0.62)、(1.84±0.46)、(2.01±0.56)mmol/L;研究组术前、术后第1天、术后第3天甲状旁腺激素分别为(58.65±3.57)、(32.24±3.77)、(46.69±4.88)pg/ml,血钙分别为(2.34±0.57)、(1.86±0.45)、(2.03±0.55)mmol/L。术前,两组患者甲状旁腺激素与血钙水平对比差异无统计学意义(P>0.05);两组患者术后第1、3天甲状旁腺激素与血钙水平均较术前有所下降,且术后第3天较术后第1天有所升高,差异有统计学意义(P<0.05);但两组患者术后第1、3天甲状旁腺激素与血钙水平对比差异无统计学意义(P>0.05)。结论 甲状旁腺即刻主动自体移植术能有效预防甲状旁腺功能的永久性减退,具有推广与应用价值。Objective To retrospectively analyze the parathyroid function between in situ preservation and immediate active autotransplantation of parathyroid glands,in order to provide reference for clinical treatment.Methods A retrospective analysis was conducted on the clinical data of 636 patients who underwent first-time surgical treatment for thyroid cancer.They were divided into a control group(517 patients who received in situ preservation of parathyroid glands)and a study group(119 patients who received immediate active autotransplantation of parathyroid glands)based on different treatment methods for the parathyroid gland.The levels of serum parathyroid hormone and blood calcium before and after surgery were compared between two groups of patients.Results In the control group,the parathyroid hormone were(58.82±3.47),(32.48±3.76),(46.86±3.65)pg/ml preoperatively and on postoperative day 1,postoperative day 3,and the blood calcium levels were(2.26±0.62),(1.84±0.46),(2.01±0.56)mmol/L.In the study group,the parathyroid hormone were(58.65±3.57),(32.24±3.77),(46.69±4.88)pg/ml preoperatively and on postoperative day 1,postoperative day 3,and the blood calcium levels were(2.34±0.57),(1.86±0.45),(2.03±0.55)mmol/L.There was no statistically significant difference in the comparison of parathyroid hormone and blood calcium levels between the two groups of patients preoperatively(P>0.05).The levels of parathyroid hormone and blood calcium in both groups decreased on postoperative day 1 and postoperative day 3,and increased on postoperative day 3 compared to postoperative day 1,with statistical significance(P<0.05).However,there was no significant difference in the level of parathyroid hormone and blood calcium between the two groups on postoperative day 1 and 3(P>0.05).Conclusion Immediate active autotransplantation of parathyroid glands can effectively prevent permanent decline in parathyroid function,which has promotion and application value.

关 键 词：甲状腺手术 甲状旁腺原位保留 甲状旁腺即刻主动自体移植术 

分 类 号：R653[医药卫生—外科学]