安胎汤联合西药治疗早期先兆流产临床研究  

Clinical Study on Antai Decoction Combined with Western Medicine for Early Threatened Abortion

作　　者：林秀伟 周荣[2] 颜晓钏[3] 王小洁[4] LIN Xiuwei;ZHOU Rong;YAN Xiaochuan;WANG Xiaojie(Department of Preventive Medicine,Wenzhou Traditional Chinese Medicine Hospital,Wenzhou Zhejiang 325000,China;Department of Neurology,Wenzhou Traditional Chinese Medicine Hospital,Wenzhou Zhejiang 325000,China;Department of Traditional Chinese Medicine Gynecology,Wenzhou Traditional Chinese Medicine Hospital,WenzhouZhejiang 325000,China;Department of Color Ultrasound Room,Wenzhou Traditional Chinese Medicine Hospital,Wenzhou Zhejiang 325000,China)

机构地区：[1]温州市中医院治未病科,浙江温州325000 [2]温州市中医院神经内科,浙江温州325000 [3]温州市中医院中医妇科,浙江温州325000 [4]温州市中医院彩超室,浙江温州325000

出　　处：《新中医》2024年第7期66-70,共5页New Chinese Medicine

摘　　要：目的:观察安胎汤联合西药治疗早期先兆流产的临床疗效。方法:采用随机数字表法将164例早期先兆流产患者分为对照组、试验组各82例。对照组予以黄体酮注射液、地屈孕酮治疗,试验组在对照组基础上加用安胎汤治疗,2组均治疗2周。比较2组治疗前后基础体温、激素水平、中医证候积分,评估2组临床疗效及妊娠结局。结果:治疗后,试验组总有效率84.15%,高于对照组70.73%(P<0.05)。治疗后,2组血清孕酮(P)、雌二醇(E_(2))、β-人绒毛膜促性腺激素(β-HCG)及基础体温水平较治疗前升高(P<0.05),中医证候积分降低(P<0.05);试验组治疗后P、E_(2)、β-HCG及基础体温水平高于对照组(P<0.05),中医证候积分低于对照组(P<0.05)。试验组流产率低于对照组(P<0.05),足月产率高于对照组(P<0.05)。2组早产率比较,差异无统计学意义(P>0.05)。结论:安胎汤联合西药治疗早期先兆流产疗效确切,能够调节患者激素水平,改善妊娠结局,提高保胎效果。Objective:To observe the clinical effect of the therapy of Antai Decoction combined with western medicine on early threatened abortion.Methods:A total of 164 patients with early threatened abortion were divided into the control group and the trial group by random number table method,with 82 patients in each group.The control group was treated with Progesterone Injection and Dydrogesterone,and the trial group was treated with Antai Decoction based on the treatment of the control group.Both groups were treated for 2 weeks.The basal body temperature,hormone levels and traditional Chinese medicine(TCM)syndrome scores in the two groups were compared before and after treatment,and the clinical effects and pregnancy outcome were evaluated in the two groups.Results:After treatment,the total effective rate was 84.15%in the trial group,higher than that of 70.73%in the control group(P<0.05).After treatment,the levels of serum progesterone(P),estradiol(E2),β-human chorionic gonadotropin(β-HCG)and basal body temperature in the two groups were increased when compared with those before treatment(P<0.05),and the TCM syndrome scores were decreased(P<0.05);after treatment,the levels of P,E2,β-HCG and basal body temperature in the trial group were higher than those in the control group(P<0.05),and the TCM syndrome scores were lower than those in the control group(P<0.05).The abortion rate in the trial group was lower than that in the control group(P<0.05),and the full-term birth rate was higher than that in the control group(P<0.05).There was no significant difference in the preterm birth rate between the two groups(P>0.05).Conclusion:The therapy of Antai Decoction combined with western medicine has a significant therapeutic effect on early threatened abortion,which can regulate the hormone levels of patients,improve the pregnancy outcome and enhance the effect of fetal protection.

关 键 词：早期先兆流产 安胎汤 基础体温 激素 妊娠结局 

分 类 号：R714.21[医药卫生—妇产科学]