补肾蠲痹汤联合针刺治疗腰椎间盘突出症致坐骨神经痛临床研究  

Clinical Study on Bushen Juanbi Decoction Combined with Acupuncture for Sciatica Caused by Lumbar Disc Herniation

作　　者：陈丹梓 蔡佳槐 林创坚 许秀玫 陈国华 CHEN Danzi;CAI Jiahuai;LIN Chuangjian;XU Xiumei;CHEN Guohua(Shantou Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine,ShantouGuangdong 515000,China;Shantou Hospital of Traditional Chinese Medicine,Shantou Guangdong 515000,China)

机构地区：[1]广州中医药大学附属汕头中医院,广东汕头515000 [2]汕头市中医医院,广东汕头515000

出　　处：《新中医》2024年第7期112-115,共4页New Chinese Medicine

基　　金：第七批全国老中医药专家学术经验继承项目(国中医药人教函[2022]76号);广东省林创坚名中医传承工作室建设项目(粤中医办函[2017]170号);广东省中医药局科研项目(20212218)。

摘　　要：目的:观察补肾蠲痹汤联合针刺治疗腰椎间盘突出症致坐骨神经痛的临床疗效。方法:60例腰椎间盘突出症致坐骨神经痛患者根据随机数字表法分为对照组、观察组各30例。对照组采用常规针刺治疗,观察组在对照组治疗基础上加用补肾蠲痹汤治疗,2组均连续治疗14 d。比较2组临床疗效及治疗前后视觉模拟评分法(VAS)评分、日本骨科协会评估治疗(JOA评分)、白细胞介素-6 (IL-6)、磷脂酶A2 (PLA2)水平。结果:治疗后,观察组总有效率90.00%,高于对照组83.33%(P<0.05)。治疗后,2组VAS评分、IL-6、PLA2水平均较治疗前降低(P<0.05),JOA评分升高(P<0.05),且观察组VAS评分、IL-6、PLA2水平低于对照组(P<0.05),JOA评分高于对照组(P<0.05)。结论:补肾蠲痹汤联合针刺治疗腰椎间盘突出症致坐骨神经痛疗效确切,能缓解患者疼痛,改善腰椎功能,抑制机体炎症反应。Objective:To observe the clinical effect of Bushen Juanbi Decoction combined with acupuncture for sciatica caused by lumbar disc herniation.Methods:A total of 60 cases of patients with sciatica caused by lumbar disc herniation were divided into the control group and the observation group according to the random number table method,with 30 cases in each group.The control group was treated with routine acupuncture,and the observation group was treated with Bushen Juanbi Decoction based on the treatment of the control group.Both groups were treated continuously for 14 days.The clinical effects and Visual Analogue Scale(VAS) scores,Japanese Orthopaedic Association(JOA) scores,and levels of interleukin-6(IL-6) and phospholipase A2(PLA2) were compared between two groups before and after treatment.Results:After treatment,the total effective rate was 90.00% in the observation group,higher than that of 83.33% in the control group(P<0.05).After treatment,the VAS scores,IL-6 and PLA2 levels in the two groups were decreased when compared with those before treatment(P<0.05),and the JOA scores were increased(P<0.05);the VAS score,IL-6 and PLA2 levels in the observation group was lower than that in the control group(P<0.05),and the JOA score was higher than that in the control group(P<0.05).Conclusion:The combination of Bushen Juanbi Decoction and acupuncture has a definite curative effect on sciatica caused by lumbar disc herniation,which can alleviate pain,improve lumbar function,and inhibit the body's inflammatory responses.

关 键 词：腰椎间盘突出症 坐骨神经痛 补肾蠲痹汤 针刺 腰椎功能 炎症因子 

分 类 号：R681.5*3[医药卫生—骨科学] R741[医药卫生—外科学]