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作 者:杨硕 刘建钗 YANG Shuo;LIU Jianchai(College of Life Science and Food Engineering,Hebei Engineering University,Handan 056038,China)
机构地区:[1]河北工程大学生命科学与食品工程学院,河北邯郸056038
出 处:《中国兽医杂志》2024年第5期146-149,共4页Chinese Journal of Veterinary Medicine
基 金:河北省重点研发计划项目(20327304D)。
摘 要:皮肤癣菌性假足菌肿是一种罕见的深层真菌感染。为了提高对此疾病的认知,本病例通过临床症状和实验室检测结果进行诊断,进而根据诊断结果用药治疗。采集患猫皮下结节样本进行细胞学检查、组织病理学检查和真菌培养。细胞学检查可见多核巨细胞和上皮样巨噬细胞吞噬蓝黑色物质和真菌菌丝;组织病理学检查结果为肉芽肿中心包含大量未着色的菌丝;真菌培养结果为犬小孢子菌的大分生孢子。综合诊断为猫皮肤癣菌性假足菌肿。治疗采用口服抗真菌药物和病灶内清创、外科切除结节相结合的方案,通过后续血常规和血清生化检查,监测口服抗真菌药物对机体造成的副作用,结果表明该患猫恢复良好,服药期间肝酶指标未见异常。Dermatophytic pseudomycetoma is a rare deep fungal infection.To enhance awareness of this disease,this case was diagnosed based on clinical symptoms and laboratory test results,followed by treatment according to the diagnosis.Subcutaneous nodular samples from the affected cat were collected for cytological examination,histopathological examination,and fungal culture.Cytological examination revealed multinucleated giant cells and epithelioid macrophages engulfing blue-black material and fungal hyphae.Histopathological examination showed a granulomatous center containing numerous unstained hyphae.Fungal culture yielded macroconidia of Microsporum canis.The comprehensive diagnosis was dermatophytic pseudomycetoma in the cat.Treatment involved a combination of oral antifungal medication and surgical excision of nodules with wound debridement.Subsequent hematological and serum biochemical tests were conducted to monitor the side effects of oral antifungal medication on the body.The results indicated a good recovery of the affected cat,with no abnormalities in liver enzyme levels during the medication period.
分 类 号:S858.292[农业科学—临床兽医学]
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