建立餐后血脂标准化评估方案推进心血管疾病防治关口前移  

Establishment of a standardized protocol for postprandial lipids assessment to promote the early prevention and treatment of cardiovascular diseases

作　　者：宁光[1] Ning Guang(Department of Endocrine and Metabolic Diseases,Shanghai Institute of Endocrine and Metabolic Diseases,National Clinical Research Center for Metabolic Diseases(Shanghai),Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China)

机构地区：[1]上海交通大学医学院附属瑞金医院内分泌代谢病科,上海市内分泌代谢病研究所,国家代谢性疾病临床医学研究中心,上海200025

出　　处：《中华内分泌代谢杂志》2024年第3期183-185,共3页Chinese Journal of Endocrinology and Metabolism

摘　　要：血脂紊乱与动脉粥样硬化的发生发展密切相关。临床实践多基于空腹血脂水平进行血脂紊乱评估,很少进行餐后肠源性脂蛋白水平的检测,进而忽视了餐后血脂异常所伴随的心血管代谢性疾病风险。作为血脂检测中不可或缺的一环,餐后血脂测定因缺乏试验餐和采血时间的统一规范而未能于临床常规开展。本期刊登的《口服脂肪耐量试验的优化研究》为解决餐后血脂测定提供了规范方法。相信未来会有更多采用此优化方法进行餐后血脂的相关研究,完善针对餐后血脂紊乱干预获益的循证医学证据,为尽早全面识别脂代谢紊乱人群以及实现心血管疾病的防治关口前移提供可靠科学依据。Dyslipidemia is closely related to the development and progression of atherosclerosis.However,current clinical practice often relies on fasting lipid levels for the assessment of dyslipidemia,with little attention given to postprandial lipid levels,thereby overlooking the cardiometabolic disease risk associated with postprandial dyslipidemia.As an indispensable component of lipid management,postprandial lipids are not routinely measured in clinical practice due to the lack of standardized protocols about test meals and blood collection program.The paper titled"Optimization of oral fat tolerance test"published in this issue proposed a standardized protocol for postprandial lipid measurement.More studies are needed to accumulate evidence about the health benefits of possible interventions and to provide a reliable scientific basis for the early identification of dyslipidemic population as well as for the prevention and treatment of cardiovascular diseases.

关 键 词：餐后血脂 心血管疾病 口服脂肪耐量试验 

分 类 号：R54[医药卫生—心血管疾病]