狭窄血管压降及壁面剪应力数值模拟分析  

Numerical simulation analysis of pressure drop and wall shear stress in stenotic vessels

作　　者：刘巍 孙傲然 刘小龙 龙丽丽 王明亮 迟青卓 张宇恒 母立众[1] LIU Wei;SUN Aoran;LIU Xiaolong;LONG Lili;WANG Mingliang;CHI Qingzhuo;ZHANG Yuheng;MU Lizhong(School of Energy and Power Engineering,Dalian University of Technology,Dalian 116024,China)

机构地区：[1]大连理工大学能源与动力学院,辽宁大连116024

出　　处：《大连理工大学学报》2024年第3期228-235,共8页Journal of Dalian University of Technology

基　　金：中央高校基本科研业务费专项资金资助项目(DUT21JC25).

摘　　要：血管狭窄是一种常见的心脑血管病变类型,狭窄血管的几何及流动参数影响着血管内压降及壁面剪应力分布.基于数值模拟分析了稳态条件下血管狭窄度、狭窄长度、偏心度及雷诺数Re对狭窄血管前后压降及壁面剪应力的影响.结果表明狭窄域压降随狭窄长度增加先减小后增大,当狭窄长度接近血管内径2倍时最小.狭窄域压降与轴反向偏心度近似成反比,与轴正向偏心度近似成正比.狭窄血管的径向偏心度越大,狭窄域压降变化幅度越大.此外,在相同狭窄度下,轴正向偏心狭窄的压降比轴反向偏心狭窄的压降更大,当Re<100时狭窄域压降与速度近似成正比,当Re>100时狭窄域压降与速度的平方近似成正比.壁面剪应力整体上随狭窄度增大而增大,在径向偏心狭窄对侧和同侧壁面剪应力大小不同,且随径向偏心度的变化也不同;轴向偏心狭窄的壁面剪应力普遍高于对心狭窄模型,且随Re的增大而增大,当Re<100时增长速度较慢,当Re>100时增长速度较快.研究将有助于评估动脉狭窄引发的血流动力学异常的风险.Vascular stenosis is a common type of cardiovascular lesion,and the geometric and flow parameters of stenotic vessels affect the intravascular pressure drop and wall shear stress distribution.The effects of the degree of stenosis,stenosis length,eccentricity and Reynolds number Re on the pressure drop and wall shear stress before and after stenotic vessels are analyzed based on numerical simulations under steady-state conditions.The results show that the pressure drop in the stenosis domain decreases first and then increases with the increase of stenosis length,and the pressure drop is the smallest when the stenosis length is close to 2 times of the internal diameter of the blood vessel.The pressure drop in the stenosis domain is approximately inversely proportional to the eccentricity of the axis in the opposite direction and approximately proportional to the eccentricity of the axis in the forward direction.The greater the radial eccentricity of the stenotic vessel,the greater the variation of pressure drop in the stenosis domain.In addition,the pressure drop of eccentric narrowing in the forward direction of the axis is larger than that in the opposite direction of the axis under the same degree of stenosis.When Re<100,the pressure drop in the stenosis domain is approximately proportional to the velocity,and when Re>100,the pressure drop in the stenosis domain is approximately proportional to the square of the velocity.As a whole,the wall shear stress increases with the increase of the degree of stenosis,and the magnitudes of the wall shear stress on the opposite side and the same side of the radial eccentric stenosis are different,and the changes with the radial eccentricity are also different.The wall shear stress of axially eccentric stenosis is generally higher than that of paracentric stenosis model,and it increases with the increase of Re.When Re<100,the growth is slower,and when Re>100,the growth is faster.The study will help to evaluate the risk of hemodynamic abnormalities caused by artery stenosis.

关 键 词：血管狭窄 压降 壁面剪应力 偏心度 

分 类 号：R318.01[医药卫生—生物医学工程]