Aggregation-Induced Catalysis: Asymmetric Catalysis with Chiral Aggregates  

作　　者：Yao Tang Yu Wang Qingkai Yuan Sai Zhang Jia-Yin Wang Shengzhou Jin Ting Xu Junyi Pan Kazimierz Surowiec Guigen Li 

机构地区：[1]Department of Chemistry and Biochemistry,Texas Tech University,Lubbock,TX 79409-1061,USA [2]School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210093,China [3]School of Pharmacy,Continuous Flow Engineering Laboratory of National Petroleum and Chemical Industry,Changzhou University,Changzhou,Jiangsu 213164,China

出　　处：《Research》2024年第1期525-532,共8页研究（英文）

基　　金：financial support from Robert A.Welch Foundation(D-1361-20210327,USA);the National Natural Science Foundation of China(nos.22071102 and 91956110).

摘　　要：So far,there have been 4 methods to control chirality including the use of chiral auxiliaries,reagents,solvents,and catalysts documented in literature and textbooks.Among them,asymmetric catalysts are normally divided into homogeneous and heterogeneous catalysis.In this report,we present a new type of asymmetric control—asymmetric catalysis via chiral aggregates that would not belong to the above categories.This new strategy is represented by catalytic asymmetric dihydroxylation reaction of olefins in which chiral ligands are aggregated by taking advantage of typical aggregation-induced emission systems containing tetrahydrofuran and H_(2)O cosolvents.It was proven that the chiral induction can be enhanced from er of 78:22 to 97:3 simply by changing the ratios of these 2 cosolvents.

关 键 词：CHIRAL ASYMMETRIC CHIRAL 

分 类 号：O62[理学—有机化学]