云南边境地区疟疾输入再传播风险和防控需求  

Malaria re-importation risk and control needs in the border region,Yunnan

作　　者：周耀武[1] 丁春丽 杨忠平 林祖锐[1] 田鹏[1] 孙晓东[1] 段凯霞 陈柒言 赵玉龙 许建卫[1] 周红宁[1] ZHOU Yaowu;DING Chunli;YANG Zhongping;LIN Zurui;TIAN Peng;SUN Xiaodong;DUAN Kaixia;CHEN Qiyan;ZHAO Yulong;XU Jianwei;ZHOU Hongning(Yunnan Institute of Parasitic Diseases,Yunnan Provincial Key Laboratory of Vector-Borne Disease Control and Research,Yunnan International Joint Laboratory of Tropical Infectious Diseases,Pu'er,Yunan 665000,China)

机构地区：[1]云南省寄生虫病防治所,云南省虫媒传染病防控重点实验室,云南省热带病国际联合实验室,云南普洱665000

出　　处：《中国热带医学》2024年第4期394-399,共6页China Tropical Medicine

基　　金：国家重点研发计划项目(No.2020YFC1200105);国家自然基金项目(No.81960374)。

摘　　要：近年来缅甸北部边境地区疟疾发病急剧回升,其中克钦邦拉咱及附近地区2023年年带虫发病率是2019年21.47(95%CI:18.84-24.48)倍,导致云南输入病例数从2019年的188例回升到2023年398例。缅北地区除军事冲突影响外,也因国际新冠疫情影响,我国与缅甸建立的边境疟疾联防联控合作机制及其疟疾控制措施得不到落实。为此,建议相关部门从技术上评估出中缅边境地区现行疟疾跨境传播措施的执行质量和效果,并针对目前缅北地区以间日疟为主的流行特点,需要提供大量能阻断疟疾传播和根治间日疟的伯氨喹啉,同时为有效减少输入疟疾病例死亡和防止输入再传播,云南边境地区仍需进一步提高临床医生疟疾诊治知识、意识和警觉性,以及中国对输入性疟疾作出适当反应的能力和质量。Recently,malaria incidence has sharply resurgence in the border area of northern Myanmar,with the parasite incidence rate in 2023 being 21.47 times(95%CI:18.84-24.48)that of 2019 in Kachin State's Razan and nearby areas.This resurgence caused the number of imported malaria cases to increase from 188 in 2019 to 398 in 2023 in Yunnan Province.In addition to the impact of military conflict,the border malaria joint prevention and control cooperation mechanism and malaria control measures established between China and Myanmar have failed to be implemented effectively due to the impact of the international COVID-19 epidemic.Hence,it is recommended that relevant departments evaluate the quality and effectiveness of the current cross-border transmission measures for malaria in the China-Myanmar border area from a technical perspective,and provide a large demand for primaquine,which can block the spread of malaria and cure vivax malaria,in response to the current prevalent characteristics of vivax malaria predominating in northern Myanmar.Moreover,to effectively reduce the mortality of imported malaria patients and prevent re-importation and transmission,it is necessary to enhance clinical physicians'knowledge,awareness,and vigilance regarding malaria diagnosis and treatment in the Yunnan border region,as well as China's ability and quality of appropriate response to imported malaria.

关 键 词：疟疾 间日疟 跨境传播 风险 边境联防联控合作 中缅边境地区 

分 类 号：R531.3[医药卫生—内科学]