我国蚊传虫媒病毒及蚊传虫媒病毒病现状及展望  

Current situation and prospect of mosquito-borne arboviruses and mosquito-borne arbovirus diseases in China

作　　者：殷启凯 付士红[1] 王环宇[1] 梁国栋[1] YIN Qikai;FU Shihong;WANG Huanyu;LIANG Guodong(National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 100052,China)

机构地区：[1]中国疾病预防控制中心病毒病预防控制所,传染病溯源预警与智能决策全国重点实验室,北京102206

出　　处：《中国热带医学》2024年第4期478-485,共8页China Tropical Medicine

基　　金：国家重点研发计划项目(No.2022YFC2305304,No.2022YFC2302700);国家自然科学基金重大项目(No.81290342)。

摘　　要：全世界已经发现300余种蚊传虫媒病毒,其中登革病毒、基孔肯雅病毒、乙脑病毒、西尼罗病毒、寨卡病毒等在世界各地流行造成巨大公共卫生负担,引起全社会广泛关注。我国地域广阔、地理景观复杂,适宜多种蚊传虫媒病毒的繁殖,因此我国蚊传虫媒病毒的种类及其地域分布等备受关注。我国自20世纪80年代起对各地采集的100余万只蚊虫和人畜动物(份)标本,利用组织细胞培养法和动物接种等方法分离鉴定出隶属于黄病毒科、布尼亚病毒科、披膜病毒科和呼肠孤病毒科等9科38种蚊传虫媒病毒。现场和实验室检测结果提示我国存在多种蚊传虫媒病毒病,包括流行性乙型脑炎、登革热、西尼罗脑炎和Tahyna病毒感染引起的发热性疾病等。本文对中国蚊传虫媒病毒、蚊传虫媒病毒与传播媒介以及蚊传虫媒病毒性传染病的种类和地域分布等进行总结,为我国蚊传虫媒病毒及其相应疾病的预防控制、疫情处理、疾病预警预测等提供了技术支撑,对亚洲乃至国际虫媒病毒病的联防联控等也具有长远和现实意义。More than 300 mosquito-borne arboviruses have been found worldwide,among which Dengue virus,Chikungunya virus,Japanese encephalitis virus,West Nile virus,and Zika virus are circulating around the world,causing a huge public health burden and arousing widespread concern in the whole society.China's vast territory and complex geographical landscapes are suitable for the reproduction of various mosquito-borne arboviruses,so the species and geographical distribution of mosquito-borne arboviruses in China have attracted much attention.Since the 1980s,38 mosquitoborne arboviruses belonging to nine families,including Flaviviridae,Bunyaviridae,Togaviridae,and Reoviridae,have been isolated and identified from more than 1 million mosquitoes and human and animal specimens collected across China by means of tissue cell culture and animal inoculation.The results of field and laboratory tests indicate the existence of various mosquitoborne arboviral diseases in China,including Japanese encephalitis,Dengue fever,West Nile encephalitis,and febrile diseases caused by Tahyna virus infection.This study summarizes the species and geographical distribution of mosquito-borne arboviruses,mosquito-borne arboviruses,and their vectors,and mosquito-borne arboviral infectious diseases in China,providing technical support for the control and prevention of mosquito-borne arbovirus and their corresponding diseases,endemic management,disease early warning and prediction.Joint prevention and control of arboviral diseases in Asia and even the world is also of long-term and practical significance.

关 键 词：蚊虫 蚊传虫媒病毒 蚊传虫媒病毒病 乙脑 登革热 

分 类 号：R511[医药卫生—内科学]