右美托咪定叠加咪达唑仑对椎管内麻醉下老年患者术中镇静及术后睡眠质量的影响  

Effects of Dexmedetomidine Combined with Midazolam on Sedation and Sleep Quality in Elderly Patients under Intraspinal Anesthesia

作　　者：李文政[1] 付晓 LI Wenzheng;FU Xiao(Department of Anesthesiology,East Hospital of Shouguang People's Hospital,Shouguang,Shandong Province,262700 China)

机构地区：[1]寿光市人民医院东院区麻醉科,山东寿光262700

出　　处：《系统医学》2024年第6期47-50,共4页Systems Medicine

摘　　要：目的分析右美托咪定叠加咪达唑仑用于椎管内麻醉手术老年患者术中镇静的效果及对其术后睡眠质量的影响。方法选取2021年1月—2023年10月寿光市人民医院东院区麻醉科开展椎管内麻醉手术的168例患者为研究对象,使用随机数表法将其分为对照组(n=84)和研究组(n=84),椎管内麻醉平面稳定后,对照组患者给予咪达唑仑维持,研究组患者给予右美托咪定联合咪达唑仑维持,比较两组生命体征指标、应激指标、术后睡眠质量和并发症发生率的差异。结果研究组患者的生命体征指标、应激指标均优于对照组,术后睡眠质量高于对照组,差异有统计学意义(P均<0.05)。研究组心动过缓、血栓、低血压、呼吸抑制、静脉血栓的总发生率为4.76%,显著低于对照组的14.29%,差异具有统计学意义(χ^(2)=4.421,P<0.05)。结论右美托咪定叠加咪达唑仑用于椎管内麻醉下老年患者术中镇静的效果突出,能够改善术后当日的睡眠质量。Objective To analyze the effect of dexmedetomidine combined with midazolam on intraoperative sedation and postoperative sleep quality in elderly patients undergoing intraspinal anesthesia.Methods A total of 168 patients who went to the Department of Anesthesiology at East Hospital of Shouguang People's Hospital for intravertebral anesthesia operation from January 2021 to October 2023 were selected as the study objects,and were divided into control group(n=84)and study group(n=84)using random number table method.After the intravertebral anesthesia level was stabilized,the control group was given midazolam maintenance,and the study group was given dexmedetomidine combined midazolam maintenance.The differences of vital signs,stress,sleep quality and complication rate were compared between two groups.Results The vital signs and stress indexes of the study group patients were better than those of the control group,and the postoperative sleep quality was higher than that of the control group,and the differences were statistically significant(all P<0.05).The total incidence of postoperative complications such as bradycardia,thrombosis,hypotension,respiratory depression and venous thrombosis of the study group was 4.76%,which was significantly lower than 14.29%in the control group,and the difference was statistically significant(χ^(2)=4.421,P<0.05).Conclusion Dexmedetomidine combined with midazolam has a prominent effect on intraoperative sedation in elderly patients under intraspinal anesthesia,and can improve the sleep quality on the day after surgery.

关 键 词：右美托咪定 咪达唑仑 椎管内麻醉 镇静效果 睡眠质量 

分 类 号：R614[医药卫生—麻醉学]