血小板参数与骨髓细胞结合用于白血病诊断的价值评估分析  

Analysis of The Value of Platelet Parameters Combined with Bone Mar⁃row Cells in the Diagnosis of Leukemia

作　　者：丛佃红 吴爱娟[2] 国岩 CONG Dianhong;WU Aijuan;GUO Yan(Clinical Laboratory,People's Hospital of Linqu County,Weifang,Shandong Province,262600 China;Departmentof Obstetrics,People's Hospital of Linqu County,Weifang,Shandong Province,262600 China;Department of Imaging,The Second People's Hospital of Linqu County,Weifang,Shandong Province,262600 China)

机构地区：[1]临朐县人民医院检验科,山东潍坊262600 [2]临朐县人民医院产科,山东潍坊262600 [3]临朐县第二人民医院影像科,山东潍坊262600

出　　处：《系统医学》2024年第6期77-80,共4页Systems Medicine

摘　　要：目的分析白血病采用血小板参数与骨髓细胞结合检验对患者病情的诊断作用及应用价值。方法选取2021年1月—2022年12月临朐县人民医院收治的72例疑似白血病患者为研究对象,采用血小板参数、骨髓细胞检验结合形式对患者实施检查,以免疫学检查、细胞遗传学检查等综合诊断结果为金标准,分析血常规检验、骨髓细胞检验结合诊断白血病的效能。结果72例患者中,综合诊断(金标准)检出白血病患者53例,血小板参数检验、骨髓细胞检验结合检验形式检出白血病患者53例,单一血小板参数检出白血病患者44例,单一骨髓细胞检验检出白血病患者49例。血小板参数、骨髓细胞检验联合对白血病诊断准确度、灵敏度分别为97.22%(70/72),98.11%(52/53),高于血小板参数检验的70.83%(51/72)、71.69%(38/53),以及骨髓细胞检验的80.56%(58/72)、83.02%(44/53),差异有统计学意义(χ^(2)=18.679、14.428、20.417、7.067,P均<0.05);各组诊断特异度相比,差异无统计学意义(P>0.05)。结论采用血小板参数、骨髓细胞检验结合检验检查、诊断白血病,能够有效明确血小板参数、骨髓细胞等指标数据,了解患者机体状态,有助于临床判断患者所患白血病类型,疾病检出率、诊断作用等。Objective To analyze the diagnostic effect and application value of platelet parameter combined with bone marrow cell test in patients with leukemia.Methods A total of 72 patients with suspected leukemia admitted to Linqu County People's Hospital from January 2021 to December 2022 were selected as the research objects,the use of platelet parameters,bone marrow cell test in combination with the form of examination,immunological examination,cytogenetic examination comprehensive diagnosis results as the gold standard.The effect of blood routine examination and bone marrow cell examination in the diagnosis of leukemia was analyzed.Results Among 72 patients,53 leukaemia patients were detected with comprehensive diagnosis(gold standard),53 leukemia patients were detected with platelet parameters test and bone marrow cell test combined with the test form,44 leukemia patients were detected by single platelet parameter,and 49 leukemia patients were detected by single bone marrow cell test.The diagnostic accuracy and sensitivity of platelet parameters and bone marrow cell test were 97.22%(70/72)respectively,98.11%(52/53),those were higher than the diagnostic efficacy of platelet parameters 70.83%(51/72)and 71.69%(38/53),and the diagnostic efficacy of bone marrow cell test 80.56%(58/72),83.02%(44/53),and the differences were statistically significant(χ^(2)=18.679,14.428,20.417,7.067,all P<0.05).There was no significant difference in diagnostic specificity of all groups(P>0.05).Conclusion In the examination and diagnosis of leukemia,the platelet parameters and bone marrow cell test combined with the test can effectively clarify the index data of platelet parameters and bone marrow cells,understand the body status of patients,and help clinical judgment of the type of leukemia patients with disease,disease detection rate and diagnostic function have significant advantages.

关 键 词：血小板参数 骨髓细胞 检验分析 白血病 诊断效能 

分 类 号：R59[医药卫生—内科学]