甲硝唑片和保妇康凝胶联合普罗雌烯乳膏治疗老年性阴道炎的效果及对炎性因子水平的影响  

Effectiveness of Metronidazole Tablets and Baofukang Gel Combined with Promestriene Cream in the Treatment of Geriatric Vaginitis and the Effect on the Levels of Inflammatory Factors

作　　者：潘月琴[1] 周丹[1] PAN Yueqin;ZHOU Dan(Department of Obstetrics and Gynecology,Jingjiang People's Hospital,Jingjiang,Jiangsu Province,214500 China)

机构地区：[1]靖江市人民医院妇产科,江苏靖江214500

出　　处：《系统医学》2024年第6期154-156,164,共4页Systems Medicine

摘　　要：目的分析甲硝唑片和保妇康凝胶联合普罗雌烯乳膏治疗老年性阴道炎的效果及对炎性因子的影响。方法选取2022年1月—2023年8月靖江市人民医院门诊接诊的86例老年性阴道炎患者为研究对象,以随机数表法分为观察组和对照组,各43例。观察组患者实施甲硝唑片和保妇康凝胶联合普罗雌烯乳膏治疗,对照组患者实施甲硝唑片及保妇康凝胶治疗,对比两组患者治疗总有效率、炎性因子水平、生活质量。结果观察组治疗总有效率为97.67%,高于对照组的81.40%,差异有统计学意义(χ^(2)=4.468,P<0.05)。干预后,观察组白细胞介素-6、肿瘤坏死因子-α、C反应蛋白分别为(48.27±12.84)ng/L、(72.63±2.42)ng/L、(30.26±8.34)mg/L,均低于对照组,差异有统计学意义(t=2.875、14.853、11.212,P均<0.05)。结论给予门诊老年性阴道炎患者甲硝唑片和保妇康凝胶联合普罗雌烯乳膏治疗效果更优,可显著改善患者症状,降低炎性因子水平。Objective To analysis the effect of metronidazole tablets and Baofukang gel combined with promestriene cream in the treatment of geriatric vaginitis and the effect on inflammatory factors.Methods 86 patients with geriatric vaginitis received by the outpatient clinic of Jingjiang People's Hospital from January 2022 to August 2023 were se lected as the study objects and were divided into the observation group and the control group,with 43 cases in each group,by the method of randomized numerical table.Patients in the observation group were treated with metronidazole tablets and Baofukang gel combined with promestriene cream,while patients in the control group were treated with metronidazole tablets and Baofukang gel.Compare the total effective rate of treatment,inflammatory factor level,qual ity of life of the two groups.Results The total effective rate of treatment in the observation group was 97.67%,which was higher than 81.40%in the control group,the difference was statistically significant(χ^(2)=4.468,P<0.05).Interleu kin-6,tumor necrosis factor-α,and C-reactive protein in the observation group were(48.27±12.84)ng/L,(72.63±2.42)ng/L and(30.26±8.34)mg/L,which were lower than those in the control group after the intervention,the differ ences were statistically significant(t=2.875,14.853,11.212,all P<0.05).Conclusion Metronidazole tablets and Bao fukang gel combined with promestriene cream given to patients with geriatric vaginitis in outpatient clinics can acheive better therapeutic effects,with significant improvement of patients'symptoms and reduction of inflammatory factor levels.

关 键 词：甲硝唑片 保妇康凝胶 普罗雌烯乳膏 门诊 老年性阴道炎 

分 类 号：R711.3[医药卫生—妇产科学]