山西省高中新生结核潜伏感染影响因素  

The influencing factors of latent tuberculosis infection among high school freshmen in Shanxi province

作　　者：朱嘉睿 范月玲[2] 商亚丽[2] 李清桃[2] 冯立忠 ZHU Jiarui;FAN Yueling;SHANG Yali;LI Qingtao;FENG Lizhong(School of Public Health,Shanxi Medical University,Taiyuan,Shanxi 030001,China;Department of Tuberculosis Prevention and Control,Shanxi Center for Disease Control and Prevention,Taiyuan,Shanxi 030012,China)

机构地区：[1]山西医科大学公共卫生学院,山西太原030001 [2]山西省疾病预防控制中心结核病防治科,山西太原030012

出　　处：《热带医学杂志》2024年第2期276-279,298,共5页Journal of Tropical Medicine

基　　金：山西省卫生健康委科研课题(2021126)。

摘　　要：目的 了解影响高一新生结核潜伏感染的因素,为制定学校结核病防治措施提供依据。方法 2021年9月开始在山西省内选取2021级入学的高一新生进行问卷调查,结合结核菌素皮肤试验(PPD)及胸部X光片结果来判断结核菌潜伏感染,分析性别、年龄、生活行为方式等因素对高中生群体结核菌潜伏感染的影响。统计分析采用χ^(2)检验和logistic回归分析。结果 研究共纳入山西省19所高中14~18岁高一新生12 908人,PPD试验强阳性102例,强阳性率为0.79%;结核菌潜伏感染102例,潜伏感染率为0.79%;胸片未见活动性肺结核患者。性别、饮酒、慢性病、结核病史、直系亲属结核病史、密切接触史、免疫系统疾病、结核病预防性治疗、结核病可疑症状均与结核菌潜伏感染有关(P均<0.05)。Logistic回归分析显示,饮酒(OR=1.741,95%CI=1.005~3.014)、慢性病史(OR=2.319,95%CI=1.453~3.702)、结核病可疑症状(OR=100.374,95%CI=54.463~184.985)是高中新生结核潜伏感染的影响因素。结论 山西省学生结核病潜伏感染率较低,饮酒、慢性病史、结核病可疑症状均与结核病潜伏感染相关,应加强对此类学生的关注,提高学生的健康素养。Objective To understand the factors affecting latent tuberculosis(TB)infection in new senior students and provide a basis for developing school⁃based tuberculosis control measures.Methods In September 2021,a questionnaire survey,purified protein derivative(PPD)skin test,and chest X⁃ray results were used to determine the latent tuberculosis infection in grade 2021 freshmen in Shanxi province.The effects of gender,age,lifestyle,and other factors on latent TB infection in high school students were analyzed.The chi⁃square test and logistic regression were used for statistical analysis.Results A total of 12908 freshmen aged 14-18 years old from 19 high schools in Shanxi province were included in the study,and 102 cases(0.79%)were strongly positive in the PPD test.The latent infection rate of 102 patients was 0.79%.Chest radiographs showed no active pulmonary tuberculosis.Gender,alcohol consumption,chronic disease,history of tuberculosis,immediate family history of tuberculosis,close contact history,immune system disease,preventive treatment of tuberculosis,and suspicious symptoms of tuberculosis were statistically associated with latent tuberculosis infection(P<0.05).Logistic regression analysis showed that alcohol consumption(OR=1.741,95%CI=1.005-3.014),chronic disease(OR=2.319,95%CI=1.453-3.702),and suspicious symptoms of tuberculosis(OR=100.374,95%CI=54.463-184.985)were the influencing factors of latent tuberculosis infection in high school freshmen.Conclusions The latent infection rate of TB among students in the Shanxi province was low.Drinking,chronic disease,and suspicious symptoms of TB were all related to latent infections of TB.More attention should be paid to these students and improve their health literacy.

关 键 词：肺结核 潜伏感染 学生 结核菌素皮肤试验 

分 类 号：R521[医药卫生—内科学]