PINK1 is involved in determining the cellular autophagic hierarchy  

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作  者:Zhuchen Zhou Zhong Chen Yanrong Zheng 

机构地区:[1]Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou 311402,China

出  处:《Science China(Life Sciences)》2024年第5期1087-1088,共2页中国科学(生命科学英文版)

基  金:supported by the National Natural Science Foundation of China (82273903)。

摘  要:The protein PINK1 plays a crucial role in the regulation of the cellular autophagic hierarchy.Autophagy,a highly conserved biological process,serves as a mechanism for the degradation of intracellular components by lysosomes.Autophagosomes play a pivotal role in this process by selectively sequestering specific targets,including damaged organelles,protein aggregates,and pathogens.

关 键 词:PINK1 DETERMINING HIERARCHY 

分 类 号:Q25[生物学—细胞生物学]

 

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