鼻疽诊断与防治技术研究进展  

Advances in diagnosis,prevention and control of glanders

作　　者：胡晓祥 熊秋婷 刘倩[1] 刘明远 方仁东[1] HU Xiaoxiang;XIONG Qiuting;LIU Qian;LIU Mingyuan;FANG Rendong(Collegeof Veterinary Medicine,Southwest University,Chongqing 400715,China;State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases/Key Laboratory of Zoonosis Research of the Ministry of Education,Institute of Zoonosis,College of Veterinary Medicine,Jilin University,Changchun 130062,China)

机构地区：[1]西南大学动物医学院,重庆北碚400715 [2]吉林大学动物医学学院人兽共患病研究所人畜共患传染病重症诊治全国重点实验室/人兽共患病研究教育部重点实验室,吉林长春130062

出　　处：《中国兽医学报》2024年第3期644-650,共7页Chinese Journal of Veterinary Science

基　　金：中央高校基本科研业务费专项资金资助项目(SWU-KQ22071);重庆市自然科学基金面上资助项目(CSTB2023NSCQ-MSX0846);重庆市高校创新研究群体资助项目(CXQT20004)。

摘　　要：鼻疽(glanders)是一种由鼻疽伯克霍尔德菌(Burkholderia mallei,B.mallei)引起,主要存在于单蹄兽中的高度传染性人兽共患病,在人类中发生病例较少。自然感染的人类病例呈现地方流行性,主要发生在接触过受感染单蹄兽的人群中。此外,实验室工作人员中也有病例报告。世界动物卫生组织(WOAH)一直在努力进行全球性的鼻疽根除工作,通过全面监测、扑杀受感染动物和采取严格进口措施,该病在北美、澳大利亚和欧洲大部分地区已被根除。然而,随着牲畜的全球性流动,导致世界其他地区的病例增加,非洲、亚洲、中东和南美洲仍然存在区域性流行。近些年来在中东和亚洲暴发的鼻疽疫情为鼻疽重新传入无疫病地区创造了可能。因此,鼻疽被归类为一种重新出现的疾病,再次威胁人类和动物健康。Glanders is a highly contagious zoonosis caused by Burkholderia mallei(B.mallei).It is mainly found in solid ungulates and rarely occurs in humans.Naturally infected human cases have been endemic,mainly among people who have been in contact with infected solid ungulates.In addition,cases have been reported among laboratory workers.The World Organisation for Animal Health(WOAH)has been working towards the global eradication of glanders,which has been eradicated in North America,Australia and most of Europe through comprehensive surveillance,culling of infected animals and strict import measures.However,the new era with the global movement of livestock has led to an increase in cases in other parts of the world,with regional epidemics still occurring in Africa,Asia,the Middle East and South America.Recent outbreaks of glanders in the Middle East and Asia have created the potential for the re-introduction of glanders into epidemic-free areas.Therefore,glanders is classified as a re-emerging disease that threatens human and animal health again.

关 键 词：鼻疽 诊断 检测 疫苗 综合防治 

分 类 号：S852.61[农业科学—基础兽医学] R535[农业科学—兽医学]