Unveiling the brain’s symphony:exploring the necessity and sufficiency of neural networks in behavior control  

作　　者：Fernando Jose Bustos 

机构地区：[1]Instituto de Ciencias Biomedicas,Facultad de Medicina y Facultad de Ciencias de la Vida,Universidad Andres Bello,Santiago,Chile [2]Millennium Nucleus of Neuroepigenetics and Plasticity(EpiNeuro),Santiago,Chile

出　　处：《Neural Regeneration Research》2025年第1期186-187,共2页中国神经再生研究（英文版）

基　　金：supported by ANID Fondecyt Iniciacion 11180540(to FJB);ANID PAI 77180077(to FJB);UNAB DI-02-22/REG(to FJB);Exploración-ANID 13220203(to FJB);ANID-MILENIO(NCN2023_23,to FJB)。

摘　　要：Since the pioneering work by Broca and Wernicke in the 19th century,who examined individuals with brain lesions to associate them with specific behaviors,it was evident that behaviors are complex and cannot be fully attributable to specific brain areas alone.Instead,they involve connectivity among brain areas,whether close or distant.At that time,this approach was considered the optimal way to dissect brain circuitry and function.These pioneering efforts opened the field to explore the necessity or sufficiency of brain areas in controlling behavior and hence dissecting brain function.However,the connectivity of the brain and the mechanisms through which various brain regions regulate specific behaviors,either individually or collaboratively,remain largely elusive.Utilizing animal models,researchers have endeavored to unravel the necessity or sufficiency of specific brain areas in influencing behavior;however,no clear associations have been firmly established.

关 键 词：behavior CONNECTIVITY neural 

分 类 号：R338[医药卫生—人体生理学]