女性冠状动脉微循环功能障碍的诊疗进展  

Progress in Diagnosis and Treatment of Coronary Microvascular Dysfunction in Women

作　　者：郭俊林[1] 文俊杰[1] 顾永林[1] 张立[2] GUO Junlin;WEN Junjie;GU Yonglin;ZHANG Li(Department of Cardiology,Guang′an People′s Hospital,Guang′an 638000,China;Department of Cardiology,West China Hospital of Sichuan University,Chengdu 610041,China)

机构地区：[1]广安市人民医院心内科,四川广安638000 [2]四川大学华西医院心内科,成都610041

出　　处：《医学综述》2024年第11期1329-1333,共5页Medical Recapitulate

基　　金：四川省科技计划项目(2017GZYZF0038)。

摘　　要：冠状动脉微循环功能障碍(CMD)是胸痛患者心肌缺血的潜在机制,其在有缺血症状和非阻塞性冠状动脉缺血的女性患者中较为常见,严重影响女性患者的生活质量及预后,与不良心血管事件增加有关。通过提高对CMD生理和病理机制的认识,可运用无创冠状动脉功能测试或侵入性冠状动脉功能测试识别相应患者并进行干预,现有的治疗措施主要改善症状和心肌血流。未来通过对该疾病的深入研究,可以更好地理解其发病机制、临床表现和诊疗策略,从而为女性患者提供更加精准、有效的治疗方法,改善患者预后,降低不良心血管事件发生风险。Coronary microvascular dysfunction(CMD)is the underlying mechanism of myocardial ischemia in patients with chest pain.CMD is relatively common in female patients with ischemic symptoms and with non-obstructive coronary ischemia,which seriously affects the quality of life and prognosis of the female patients,and is associated with increased adverse cardiovascular events.By improving the understanding of physiological mechanism and pathological mechanism of CMD,non-invasive coronary function test or invasive coronary function test can be used to identify the patients and administer corresponding interventions,and existing treatment measures mainly improve the symptoms and myocardial blood flow.In the future,through the further studies of the disease,better understandings of its pathogenesis,clinical manifestations and diagnosis and treatment strategy can be gained,to provide more accurate and effective treatment,improve prognosis,and reduce the risk of adverse cardiovascular events of the female patients.

关 键 词：冠状动脉微循环功能障碍 冠状动脉功能测试 冠状动脉血流储备 非阻塞性冠状动脉缺血 

分 类 号：R543.3[医药卫生—心血管疾病]