髓过氧化物酶和脂蛋白相关磷脂酶A_(2)与急性冠状动脉综合征关系的研究进展  

Research Progress in Relationship of Myeloperoxidase and Lipoprotein-associated Phospholipase A_(2) with Acute Coronary Syndrome

作　　者：王晓迪 图尔荪古丽·多力坤 李幸 王玉玲[2] WANG Xiaodi;TUERSUNGULI Duolikun;LI Xing;WANG Yuling(Department of Emergency Trauma Center,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,China;Department of Cadre Health Center,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,China)

机构地区：[1]新疆医科大学第一附属医院急救创伤中心,乌鲁木齐830000 [2]新疆医科大学第一附属医院干部保健中心,乌鲁木齐830000

出　　处：《医学综述》2024年第11期1377-1381,1388,共6页Medical Recapitulate

基　　金：新疆维吾尔自治区科技支疆项目计划(指令性)项目(2021E02068)。

摘　　要：心血管疾病是全球死亡的主要原因。急性冠状动脉综合征(ACS)作为一种临床心脏急症,及时开通病变血管能够明显改善患者预后。对于胸痛患者,如果能够在初期尽早鉴别ACS并采取精准处理措施,将会极大地降低患者的死亡风险,同时改善患者预后。近年来,髓过氧化物酶(MPO)和脂蛋白相关磷脂酶A_(2)(Lp-PLA_(2))与ACS之间关系的研究取得了一定进展,这有助于深入理解ACS的发病机制,对ACS的发生、发展及预后评估有明显预测价值。未来深入研究MPO和Lp-PLA_(2)与ACS的关系将为ACS患者的治疗和预后提供临床借鉴。Cardiovascular disease is the leading cause of global mortality.For acute coronary syndrome(ACS),a clinical cardiac emergency,timely opening of diseased blood vessels can significantly improve the patient prognosis.For patients with chest pain,if ACS can be identified early and precise treatment measures can be taken,it will greatly reduce the risk of death and improve the prognosis of the patients.In recent years,research on the relationship of myeloperoxidase(MPO)and lipoprotein-associated phospholipase A_(2)(Lp-PLA_(2))with ACS has made certain progress,which helps to deepen the understanding of the pathogenesis of ACS and has significant predictive value for the occurrence,development,and prognosis evaluation of ACS.In the future,in-depth research on the relationship of MPO and Lp-PLA_(2)with ACS will provide clinical reference for the treatment and prognosis of ACS patients.

关 键 词：急性冠状动脉综合征 髓过氧化物酶 脂蛋白相关磷脂酶A_(2) 

分 类 号：R541[医药卫生—心血管疾病]