抗-E、抗-c、抗-M、抗-S多重抗体分析  

Multiple antibodies against-E,-c,-M,and-S:a case report

作　　者：高娃[1] 李冰[1] 班凤禹 王秋实[1] GAO Wa;LI Bing;Ban Fengyu;WANG Qiushi(Blood Transfusion Department,Shengjing Hospital Affiliated to China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院输血科,辽宁沈阳110004

出　　处：《中国输血杂志》2024年第5期511-515,533,共6页Chinese Journal of Blood Transfusion

基　　金：辽宁省科技厅重点研发计划课题(2021JH2-10300045)。

摘　　要：目的对1例存在多重抗体的肾积水伴输尿管结石合并休克老年患者进行抗体特异性鉴定。方法微柱凝胶法进行红细胞不规则抗体筛查和抗体鉴定,酶法,抗体吸收法协助判断患者的抗体特异性;盐水试管法检测患者ABO血型鉴定、Rh血型鉴定、MNS血型。结果患者血型:O、CCDee、NNss,患者体内检测出抗-E、抗-c、抗-M、抗-S联合抗体。结论反复输血可能引起患者存在1种或者多种意外抗体,体内多种或高频率抗体的患者,可能引起鉴定困难和用血延迟。Objective To identify antibody specificity in an elderly patient with hydronephrosis accompanied by ureteral stones and shock who had multiple antibodies.Methods Microcolumn gel method was used to screen unexpected antibodies of red blood cells and identify antibodies.Enzyme method and antibody absorption method were used to help judge the specificity of antibodies in patients.The ABO blood type,Rh blood type and MNS blood type of patient were determined by saline tube method.Results The patient′s blood types were O,CCDee,NNss,and a combination of anti-E,anti-c,anti-M and anti-S antibodies was detected.Conclusion Repeated blood transfusion may lead to the presence of one or more unexpected antibodies in patients.Patients with multiple or high-frequency antibodies may experience difficulties in identification and delayed blood use.

关 键 词：多重抗体 抗体鉴定 

分 类 号：R457.11[医药卫生—治疗学]