低效价O型全血在国外创伤救治中的应用进展  

Recognition of whole blood transfusion in civilian trauma resuscitation

作　　者：马维娟 任少敏 杨忠思 张燕华 MA Weijuan;REN Shaomin;YANG Zhongsi;ZHANG Yanhua(Qingdao Blood Center,Qingdao 266071,China)

机构地区：[1]青岛市中心血站,山东青岛266071

出　　处：《中国输血杂志》2024年第5期602-606,共5页Chinese Journal of Blood Transfusion

摘　　要：越来越多的证据表明,红细胞、新鲜冰冻血浆和血小板平衡配比的成分输血在创伤患者大量输血复苏中效果更好,这重新激发了在大量输血方案中使用全血的关注,多数欧美国家大型创伤中心已在院前急救中常规使用低效价O型全血。迄今为止越来越多证据支持危及生命大出血患者早期使用低效价O型全血可提高其生存率。鉴于我国全血的供应现状,多数创伤救治指南在复苏早期大量输血方案中仍推荐平衡配比成分输血。我们对国外低效价O型全血研究使用情况作一介绍。There has been a growing amount of evidence that a balanced blood component transfusion with roughly equal ratio of units of packed red blood cells,fresh frozen plasma,and platelets leads to better outcomes in massive transfusion resuscitation of trauma victims.Therefore,the great interest of massive transfusion protocol(MTP)with whole blood was aroused.Low titer group O whole blood(LTOWB)is implemented in routine use for civilian prehospital ambulance services in large trauma centers of most European and American countries nowadays.There is a growing body of evidence to date to support that early use of LTOWB in patients with life-threatening bleeding improve their survival.In view of the current situation of whole blood supply in our country,most trauma resuscitation guidelines still recommend balanced component transfusion for MTPs in the early stage of resuscitation.The research and application of LTOWB abroad will be introduced in this article.

关 键 词：全血 低效价O型全血 成分输血 大量输血方案 损伤控制复苏 

分 类 号：R457.1[医药卫生—治疗学]