樟树5种化学型精油组成及其胰脂肪酶抑制活性研究  

Study on Composition and Pancreatic lipase Inhibition Activity of Five Chemotype Essential Oils ofCamphor Tree

作　　者：杨海宽[1] 邱凤英[1] 温世钫 YANG Hai-kuan;QIU Feng-ying;WEN Shi-fang(Camphor Engineering and Technology Research Center for State Forestry and Grass Administration,Jiangxi Academy of Forestry,Nanchang 330032,China)

机构地区：[1]江西省林业科学院国家林业和草原樟树工程技术研究中心,江西南昌330032

出　　处：《精细化工中间体》2024年第2期46-50,共5页Fine Chemical Intermediates

基　　金：江西省科技厅重大科技研发专项:我国南方香料樟树高效种植与精深加工全产业链关键技术研究与开发(20203ABC28W016)。

摘　　要：采用GC和GC-MS方法分析确定了樟树5种精油化学成分组成,进一步研究了5种不同类型精油的胰脂肪酶抑制活性。结果表明:5种精油主成分分别为:芳樟醇(91.98%)、樟脑(81.25%)、龙脑(91.88%)、反式-橙花叔醇(52.63%)和桉叶油素(57.73%)。精油的胰脂肪酶抑制活性顺序为:反式-橙花叔醇型>桉叶油素型>芳樟醇型>樟脑型>龙脑型。其中反式-橙花叔醇型精油IC50为(20.02±3.27)mg/mL,当其精油浓度为100 mg/mL时,胰脂肪酶抑制率达90.17%±1.56%。Chemical composition of five different chemotype essential oils from camphor tree was tested using GC and GC-MS methods.The results indicated that the high content components among the five chemotype of essential oils were linalool(91.98%),camphor(81.25%),borneol(91.88%),trans-nerolidol(52.63%)and eucalyptol(57.73%).Moreover,pancreatic lipase inhibitory activity of different chemotype essential oils was also studied.The pancreatic lipase inhibition activity of essential oils showed that the comparison of chemotype was as follows:trans-nerolidol chemotype>eucalyptol chemotype>linalool chemotype>camphor chemotype>borneol chemotype.The IC50 value of trans-nerolidol chemotype was(20.02±3.27)mg/mL,and the enzyme inhibition ratio can reach up to 90.17%±1.56%on concentration of 100 mg/mL.

关 键 词：樟树 精油 组成 胰脂肪酶抑制 

分 类 号：TQ914[化学工程]