Increased number of symptoms during the acute phase of SARS-CoV-2 infection in athletes is associated with prolonged time to return to full sports performance—AWAREⅧ  

作　　者：Carolette Snyders Marlise Dyer Nicola Sewry Esme Jordaan Martin Schwellnus 

机构地区：[1]Sport,Exercise Medicine and Lifestyle Institute(SEMLI),Faculty of Health Sciences,University of Pretoria,Pretoria 0083,South Africa [2]Section Sports Medicine,Faculty of Health Sciences,University of Pretoria,Pretoria 0083,South Africa [3]IOC Research Centre of South Africa,Pretoria 0083,South Africa [4]Biostatistics Unit,South African Medical Research Council,Tygerberg 7505,South Africa [5]Statistics and Population Studies Department,University of the Western Cape,Cape Town 7535,South Africa

出　　处：《Journal of Sport and Health Science》2024年第3期280-287,I0001,共9页运动与健康科学（英文）

基　　金：supported by funding from the International Olympic Committee(IOC);CS received a scholarship made possible through funding by the South African Medical Research Council(SAMRC)through its Division of Research Capacity Development under the SAMRC Clinician Researcher Programme;Research reported in this publication was also supported by the SAMRC under a Self-Initiated Research Grant to MS.

摘　　要：Purpose The aim of the study was to identify factors associated with prolonged time to return to full performance(RTFP)in athletes with recent severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection.Methods Prospective cohort study with cross sectional analysis.A total of 84 athletes with confirmed SARS-CoV-2 infection assessed at a coronavirus disease 2019 recovery clinic gave a history of age,sex,type/level of sport,co-morbidities,pre-infection training hours,and 26 acute SARS-CoV-2 symptoms from 3 categories(“nose and throat”,“chest and neck”,and“whole body”/systemic).Data on days to RTFP were obtained by structured interviews.Factors associated with RTFP were demographics,sport participation,history of co-morbidities,pre-infection training history,and acute symptoms(type,number).Outcomes were:(a)days to RTFP(median,interquartile range(IQR))in asymptomatic(n=7)and symptomatic athletes(n=77),and(b)hazard ratios(HRs;95%confidence interval)for symptomatic athletes with vs.without a factor(univariate,multiple models).HR<1 was predictive of higher percentage chance of prolonged RTFP.Significance was p<0.05.Results Days to RTFP were 30 days(IQR:23–40)for asymptomatic and 64 days(IQR:42–91)for symptomatic participants(p>0.05).Factors associated with prolonged RTFP(univariate models)were:females(HR=0.57;p=0.014),endurance athletes(HR=0.41;p<0.0001),co-morbidity number(HR=0.75;p=0.001),and respiratory disease history(HR=0.54;p=0.026).In symptomatic athletes,prolonged RTFP(multiple models)was significantly associated with increased“chest and neck”(HR=0.85;p=0.017)and“nose and throat”(HR=0.84;p=0.013)symptoms,but the association was more profound between prolonged RFTP and increased total number of“all symptoms”(HR=0.91;p=0.001)and“whole body”/systemic(HR=0.82;p=0.007)symptoms.Conclusion A larger number of total symptoms and specifically“whole body”/systemic symptoms during the acute phase of SARS-CoV-2 infection in athletes is associated with prolonged RTFP.

关 键 词：ATHLETES COVID-19 Performance Recovery Return to play 

分 类 号：R511[医药卫生—内科学] G804.2[医药卫生—临床医学]