血清免疫球蛋白E过敏原检测在小儿毛细支气管炎中的临床意义  

Clinical significance of serum immunoglobulin E allergen detection in children with bronchiolitis

作　　者：宋振香 SONG Zhenxiang(Department of Laboratory,Zibo Maternal and Child Health Hospital,Shandong Province,Zibo 255000,China)

机构地区：[1]山东省淄博市妇幼保健院检验科,山东淄博255000

出　　处：《妇儿健康导刊》2024年第9期72-75,共4页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

摘　　要：目的 探讨血清免疫球蛋白E(IgE)过敏原检测在小儿毛细支气管炎中的临床意义。方法 选取2022年5月至2023年5月于淄博市妇幼保健院确诊为毛细支气管炎的60例患儿为观察组,按照病情严重程度分为观察1组(24例,轻度)、观察2组(20例,中度)、观察3组(16例,重度);选取同期60例健康儿童为对照组。比较对照组与观察组的IgE水平,并比较观察1组、观察2组、观察3组的IgE水平,分析小儿毛细支气管炎与IgE水平的相关性。结果 观察组IgE水平高于对照组(P <0.05);观察3组IgE水平高于观察1组和观察2组,观察2组IgE水平高于观察1组(P <0.05);小儿毛细支气管炎严重程度与IgE水平呈正相关(r=0.895,P <0.001)。结论 毛细支气管炎患儿的血清IgE水平较高,且与病情严重程度呈正相关,可用于毛细支气管炎的病情评估。Objective To investigate the clinical significance of serum immunoglobulin E(IgE)allergen detection in children with bronchiolitis.Methods A total of 60 children diagnosed with bronchiolitis in Zibo Maternal and Child Health Hospital from May 2022 to May 2023 were selected as the observation group.According to the severity of the disease,they were divided into observation group 1(24 cases,mild),observation group 2(20 cases,moderate),and observation group 3(16 cases,severe).At the same time,60 healthy children were selected as the control group.The IgE level of the control group and the observation group was compared,and the IgE level of observation group 1,observation group 2,and observation group 3 was compared,the correlation between the IgE level and pediatric bronchiolitis was analyzed.Results The IgE level in the observation group was higher than that in the control group(P<0.05).The IgE level in the observation group 3 was higher than that in the observation group 1 and observation group 2,and the IgE level in the observation group 2 was higher than that in the observation group 1(P<0.05).The IgE level was positively correlated with the severity of bronchiolitis in children(r=0.895,P<0.001).Conclusion Serum IgE level in children with bronchiolitis is higher and positively correlated with the severity of the disease,which can be used for the evaluation of bronchiolitis.

关 键 词：免疫球蛋白E 小儿毛细支气管炎 相关性 

分 类 号：R725.6[医药卫生—儿科]