基于肠肝轴理念探讨“凡十一脏取决于胆”与2型糖尿病关系  

Exploring the Theory that"All 11 Zang-organs Dominated by Gallbladder"Based on the Intestinal-liver Axis association with Type 2 Diabetes

作　　者：曾施琪 陈文辉[2] 李双蕾[2] 蒋云霞 白蕊[3] 金鑫艳 王婷[1] 郑洪香 贾洪洋 ZENG Shiqi;CHEN Wenhui;LI Shuanglei;JIANG Yunxia;BAI Rui;JIN Xinyan;WANG Ting;ZHENG Hongxiang;JIA Hongyang(Guangxi University of Chinese Medicine,Nanning 530001,Guangxi,China;The First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530023,Guangxi,China;Science College of New Medicine Affiliated to Guangxi University of Chinese Medicine,Nanning 530222,Guangxi,China)

机构地区：[1]广西中医药大学,广西南宁530001 [2]广西中医药大学第一附属医院,广西南宁530023 [3]广西中医药大学赛恩斯新医药学院,广西南宁530222

出　　处：《实用中医内科杂志》2024年第5期18-21,共4页Journal of Practical Traditional Chinese Internal Medicine

基　　金：国家自然科学基金地区基金项目(81860784);广西高等教育本科教学改革工程项目(2021JGZ182);广西中医药大学研究生教育创新计划项目(YCSY2022022)。

摘　　要：中医认为“凡十一脏取决于胆”,胆在消渴发生发展中起重要作用,主要通过:(1)胆主决断,调控人体精神活动;(2)和解少阳枢机;(3)主少阳春升之气;这三个环节调控人体的新陈代谢。若枢机失常,气血不畅,则气滞、痰凝、血瘀产生,进而发为消渴。现代医学发现“肠-肝轴”与2型糖尿病发病密切相关,其内在机制可能与肠道机械屏障破坏通透性增加、化学屏障不足代谢失常、生物屏障失调能量紊乱等因素相关。因此,从“胆”出发辨证论治,结合“肠-肝轴”功能特点,为2型糖尿病的治疗提供了一个新视角。Traditional Chinese medcine believes that"All 11 Zang-organs are dominated by gallbladder".The gallbladder plays an important role in the occurrence and development of diabetes,mainly about:the gallbladder masters the mental activities of the human body.The gallbladder is the key point to the reconciliation of the exercise of qi.The gallbladder produces a rising qi of Shaoyang,these three links regulate the metabolism of the human body.If the qi movement is not in order,the qi stagnation,phlegm coagulation,and blood stasis are produced,and then Xiaoke happens.Modern medicine has found that the"intestinal-liver axis"is closely related to the development of type 2 diabetes mellitus and its internal mechanism may be related to the destruction of the intestinal mechanical barrier and the increase of permeability,the lack of chemical barrier and metabolic disorders,biological barrier disorders,energy disorders,and other factors.Therefore,the dialectical treatment from the"gallbladder",combined with the functional characteristics of the"intestinal-liver axis",provides a new perspective for treating type 2 diabetes mellitus.

关 键 词：2型糖尿病 肠肝轴 凡十一脏取决于胆 理论探讨 

分 类 号：R259[医药卫生—中西医结合]