“天枢-带脉”电针法结合行为控制治疗代谢相关脂肪性肝病的疗效观察  

Observation of the efficacy of"Tianshu-Belt Vessel"electroacupuncture combined with behavioral control in the treatment of non-alcoholic fatty liver disease

作　　者：李德恒 郭瑞 LI De-heng;GUO Rui(Department of Hepatology,Hainan Western Central Hospital,Hainan 571700,China)

机构地区：[1]海南西部中心医院肝病科,571700 [2]中国中医科学院西苑医院治未病中心,100091

出　　处：《中国实用医药》2024年第9期117-120,共4页China Practical Medicine

摘　　要：目的对“天枢-带脉”电针法结合行为控制治疗代谢相关脂肪性肝病(NAFLD)的疗效观察和讨论。方法选取80例NAFLD患者,随机分为治疗组(“天枢-带脉”电针法结合行为控制)与对照组(行为控制),各40例。比较两组患者临床疗效,治疗前后体质量指数(BMI)及肝功能指标[谷草转氨酶(AST)、谷丙转氨酶(ALT)],治疗前后血脂指标[低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、甘油三酯(TG)、总胆固醇(TC)]。结果治疗组患者的治疗总有效率90.0%高于对照组的60.0%,差异具有统计学意义(P<0.05)。治疗组治疗前BMI、ALT、AST分别为(26.30±1.32)kg/m^(2)、(69.42±14.89)U/L、(56.31±13.25)U/L,治疗后分别为(24.25±1.16)kg/m^(2)、(43.50±9.89)U/L、(41.05±11.87)U/L;对照组治疗前BMI、ALT、AST分别为(26.42±1.45)kg/m^(2)、(68.99±15.37)U/L、(55.89±11.08)U/L,治疗后分别为(24.85±1.13)kg/m^(2)、(56.24±13.05)U/L、(47.89±10.67)U/L。治疗后,两组患者的BMI、ALT、AST水平均较治疗前下降,治疗组的BMI、ALT、AST水平下降程度较对照组显著(P<0.05)。治疗组治疗前TC、TG、HDL-C、LDL-C分别为(6.23±0.49)、(3.29±0.47)、(0.87±0.49)、(3.57±0.59)mmol/L,治疗后分别为(4.58±0.56)、(1.05±0.61)、(1.49±0.35)、(2.49±0.48)mmol/L;对照组治疗前TC、TG、HDL-C、LDL-C分别为(6.40±0.54)、(3.41±0.83)、(0.86±0.36)、(3.58±0.62)mmol/L,治疗后分别为(5.07±0.25)、(1.31±0.58)、(1.01±0.38)、(2.95±0.41)mmol/L。治疗后,两组患者的TG、TC和LDL-C水平均较治疗前下降,治疗组的HDL-C显著较治疗前升高(P<0.05);而对照组治疗后HDL-C较治疗前差异不显著(P>0.05);治疗后,治疗组患者TC、LDL-C水平低于对照组,HDL-C水平高于对照组,差异有统计学意义(P<0.05);两组治疗后TG水平差异不显著(P>0.05)。结论“天枢-带脉”电针法结合行为控制治疗NAFLD的临床疗效显著,患者可获得病情逆转,同时肝功能及血脂显著受益。Objective To observe and discuss the efficacy of"Tianshu-Belt Vessel"electroacupuncture combined with behavioral control in the treatment of non-alcoholic fatty liver disease(NAFLD).Methods A total of 80 patients with NAFLD were selected and randomly divided into a treatment group("Tianshu-Belt Vessel"electroacupuncture combined with behavioral control)and a control group(behavioral control),each with 40 cases.Patients in both groups were compared in terms of clinical efficacy,body mass index(BMI)and liver function indexes[aspartate transaminase(AST),alanine aminotrasferase(ALT)]before and after treatment,and blood lipid indexes[low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),triglyceride(TG),total cholesterol(TC)]before and after treatment.Results The treatment group had higher total effective rate of 90.0%than 60.0%in the control group,and the difference was statistically significant(P<0.05).In the treatment group,BMI,ALT and AST before treatment were(26.30±1.32)kg/m^(2),(69.42±14.89)U/L and(56.31±13.25)U/L;after treatment,they were(24.25±1.16)kg/m^(2),(43.50±9.89)U/L and(41.05±11.87)U/L.In the control group,BMI,ALT and AST before treatment were(26.42±1.45)kg/m^(2),(68.99±15.37)U/L and(55.89±11.08)U/L;after treatment,they were(24.85±1.13)kg/m^(2),(56.24±13.05)U/L and(47.89±10.67)U/L.After treatment,the levels of BMI,ALT and AST in both groups decreased compared with those before treatment,and the levels of BMI,ALT and AST in the treatment group decreased significantly compared with those in the control group(P<0.05).In the treatment group,TC,TG,HDL-C and LDL-C before treatment were(6.23±0.49),(3.29±0.47),(0.87±0.49)and(3.57±0.59)mmol/L;after treatment,they were(4.58±0.56),(1.05±0.61),(1.49±0.35)and(2.49±0.48)mmol/L.In the control group,TC,TG,HDL-C and LDL-C before treatment were(6.40±0.54),(3.41±0.83),(0.86±0.36)and(3.58±0.62)mmol/L;after treatment,they were(5.07±0.25),(1.31±0.58),(1.01±0.38)and(2.95±0.41)mmol/L.After treatment,the levels of TG,

关 键 词：代谢相关脂肪性肝病 电针 天枢-带脉穴 行为控制 

分 类 号：R246.1[医药卫生—针灸推拿学]